NA 0346 | CAS#120925-61-3 | Antihypertensive Compound

MedKoo Cat#: 110220 | Name: NA 0346

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NA 0346 is a derivative of SF 2370 that shows long lasting antihypertensive action as well as potent protein kinases inhibitory activity.

Chemical Structure

NA 0346

CAS#120925-61-3

Theoretical Analysis

MedKoo Cat#: 110220

Name: NA 0346

CAS#: 120925-61-3

Chemical Formula: C26H22N4O3

Exact Mass: 438.1692

Molecular Weight: 438.49

Elemental Analysis: C, 71.22; H, 5.06; N, 12.78; O, 10.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NA 0346; NA0346; NA-0346

IUPAC/Chemical Name

9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocin-1-one, 10-(aminomethyl)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-, (9S-(9alpha,10beta,12alpha))-

InChi Key

GAXOKIHBYAPTSY-LROUJFHJSA-N

InChi Code

InChI=1S/C26H22N4O3/c1-25-26(32,12-27)10-18(33-25)29-16-8-4-2-6-13(16)20-21-15(11-28-24(21)31)19-14-7-3-5-9-17(14)30(25)23(19)22(20)29/h2-9,18,32H,10-12,27H2,1H3,(H,28,31)/t18-,25+,26+/m1/s1

SMILES Code

C[C@]12[C@](CN)(O)C[C@](O2)([H])N3C4=CC=CC=C4C5=C6C(CN=C6O)=C7C8=CC=CC=C8N1C7=C53

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 438.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Hachisu M, Hiranuma T, Koyama M, Sezaki M. Antihypertensive compounds with potent protein kinases inhibitory activity. Life Sci. 1989;44(19):1351-62. doi: 10.1016/0024-3205(89)90392-5. PMID: 2765030.