Epitinib, also known as HMPL813, is an orally available epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. Upon administration, epitinib inhibits the activity of EGFR, thereby preventing EGFR-mediated signaling. This may lead to induction of cell death and inhibition of tumor growth in EGFR-overexpressing tumor cells.
MedKoo Cat#: 414046
Name: Epitinib succinate
CAS#: 2252334-12-4 (succinate)
Chemical Formula: C28H32N6O6
Exact Mass: 548.2383
Molecular Weight: 548.60
Elemental Analysis: C, 61.30; H, 5.88; N, 15.32; O, 17.50
The following data is based on the product molecular weight 548.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
