Epitinib, also known as HMPL813, is an orally available epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. Upon administration, epitinib inhibits the activity of EGFR, thereby preventing EGFR-mediated signaling. This may lead to induction of cell death and inhibition of tumor growth in EGFR-overexpressing tumor cells.
MedKoo Cat#: 414045
Name: Epitinib Free Base
CAS#: 1203902-67-3 (free base)
Chemical Formula: C24H26N6O2
Exact Mass: 430.2117
Molecular Weight: 430.51
Elemental Analysis: C, 66.96; H, 6.09; N, 19.52; O, 7.43
The following data is based on the product molecular weight 430.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
