ZYN57939 is RNA polymerase I inhibitor for treating RNA polymerase I-mediated diseases. ZYN57939 was first reported in CN 104177379 A 20141203 (2014). ZYN57939 showed inhibitory activity with IC50 of 0.855 μM against human HT-29 cancer cell lines. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 555989
Name: ZYN57939
CAS#: 1639357-93-9
Chemical Formula: C29H28N6O2S
Exact Mass: 524.1994
Molecular Weight: 524.64
Elemental Analysis: C, 66.39; H, 5.38; N, 16.02; O, 6.10; S, 6.11
The following data is based on the product molecular weight 524.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
