Pynegabine, also known as HN-37, is a novel potent antiepileptic agent, exhibiting enhanced activation potency toward neuronal Kv7 channels and high in vivo efficacy in a range of pre-clinical seizure models, including the maximal electroshock test and a 6 Hz model of pharmacoresistant limbic seizures.
MedKoo Cat#: 464636
Name: Pynegabine
CAS#: unknown
Chemical Formula: C20H21FN2O2
Exact Mass: 340.1587
Molecular Weight: 340.40
Elemental Analysis: C, 70.57; H, 6.22; F, 5.58; N, 8.23; O, 9.40
The following data is based on the product molecular weight 340.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
