UCN96511, also known as 5'-O-DMT-Thymidine-CE Phosphoramidite, is a thymidine-derived nucleotide phosphoramidite used in solid-phase DNA synthesis. The 5'-O-dimethoxytrityl (DMT) group serves as a temporary protecting group, allowing controlled nucleotide addition, while the cyanoethyl (CE) phosphoramidite moiety facilitates efficient phosphodiester bond formation during oligonucleotide elongation. This reagent is essential for synthesizing oligonucleotides with precise sequence control, particularly in automated DNA synthesis protocols. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 122592
Name: UCN96511
CAS#: 98796-51-1
Chemical Formula: C40H49N4O8P
Exact Mass: 744.3300
Molecular Weight: 744.83
Elemental Analysis: C, 64.50; H, 6.63; N, 7.52; O, 17.18; P, 4.16
The following data is based on the product molecular weight 744.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
