Zeteletinib, also known as BOS-172738, DS-5010), is an orally bioavailable selective inhibitor of wild-type, fusion products and mutated forms, including gatekeeper mutations, of the proto-oncogene receptor tyrosine kinase rearranged during transfection (RET), with potential antineoplastic activity.
MedKoo Cat#: 413045
Name: Zeteletinib free base
CAS#: 2216753-97-6 (free base)
Chemical Formula: C25H23F3N4O4
Exact Mass: 500.1671
Molecular Weight: 500.48
Elemental Analysis: C, 60.00; H, 4.63; F, 11.39; N, 11.19; O, 12.79
The following data is based on the product molecular weight 500.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
