ICI-116258 | CAS# 102904-11-0 | Biochemical

MedKoo Cat#: 576525 | Name: ICI-116258

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI-116258 is an anti-inflammatory prodrug.

Chemical Structure

ICI-116258

CAS#102904-11-0

Theoretical Analysis

MedKoo Cat#: 576525

Name: ICI-116258

CAS#: 102904-11-0

Chemical Formula: C27H35ClN2O6

Exact Mass: 518.2184

Molecular Weight: 519.03

Elemental Analysis: C, 62.48; H, 6.80; Cl, 6.83; N, 5.40; O, 18.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ICI 116258; ICI116258; ICI-116258

IUPAC/Chemical Name

Propanoic acid, 2,2-dimethyl-, 4-(2-((2-((4-chlorobenzoyl)amino)ethyl)amino)-1-hydroxyethyl)-1,2-phenylene ester

InChi Key

OCJAVPIJUPKLSM-UHFFFAOYSA-N

InChi Code

InChI=1S/C27H35ClN2O6/c1-26(2,3)24(33)35-21-12-9-18(15-22(21)36-25(34)27(4,5)6)20(31)16-29-13-14-30-23(32)17-7-10-19(28)11-8-17/h7-12,15,20,29,31H,13-14,16H2,1-6H3,(H,30,32)

SMILES Code

CC(C)(C)C(=O)Oc1ccc(cc1OC(=O)C(C)(C)C)C(O)CNCCNC(=O)c2ccc(Cl)cc2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 519.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Bilski AJ, Evans JR, Harrison MP, Jones G, Marten TR, Milburn GT, Thomson DS, White DF. Lipoidal anti-inflammatory prodrugs as local targeting agents. Biochem Soc Trans. 1986 Apr;14(2):388-91. doi: 10.1042/bst0140388. PMID: 3011550.