ICI-147798 HCl | CAS# 86015-39-6 | Biochemical

MedKoo Cat#: 576488 | Name: ICI-147798 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI-147798 HCl is a beta adrenoceptor antagonist.

Chemical Structure

ICI-147798 HCl

CAS#86015-39-6

Theoretical Analysis

MedKoo Cat#: 576488

Name: ICI-147798 HCl

CAS#: 86015-39-6

Chemical Formula: C24H31Cl2N7O4

Exact Mass: 551.1815

Molecular Weight: 552.46

Elemental Analysis: C, 52.18; H, 5.66; Cl, 12.83; N, 17.75; O, 11.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ICI-147798 hydrochloride; ICI-147798 HCl; ICI 147798 HCl; ICI147798 HCl

IUPAC/Chemical Name

3,5-Diamino-6-chloro-N-(2-((2-((2-hydroxy-3-(1-naphthalenyloxy)propyl)amino)ethyl)amino)-1,1-dimethyl-2-oxoethyl)-2-pyrazinecarboxamide hydrochloride

InChi Key

FPYKIVKAYUQLGA-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H30ClN7O4.ClH/c1-24(2,32-22(34)18-20(26)31-21(27)19(25)30-18)23(35)29-11-10-28-12-15(33)13-36-17-9-5-7-14-6-3-4-8-16(14)17;/h3-9,15,28,33H,10-13H2,1-2H3,(H,29,35)(H,32,34)(H4,26,27,31);1H

SMILES Code

Cl.CC(C)(NC(=O)c1nc(Cl)c(N)nc1N)C(=O)NCCNCC(O)COc2cccc3ccccc23

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 552.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Keith RA, Hwang TF, Murthy VS, Kau ST, Salama AI, Giles RE. ICI 147,798: a slowly dissociable beta adrenoceptor antagonist that causes insurmountable beta-1 and surmountable beta-2 adrenoceptor antagonism in isolated tissues. J Pharmacol Exp Ther. 1989 Jan;248(1):240-8. PMID: 2563288.