Synonym
WYM76507; WYM-76507; WYM 76507; Mn(III) meso-Tetra(4-sulfonatophenyl)porphine chloride (acid form)
InChi Key
WMITXTXHDITCGT-YKKPBKTHSA-M
InChi Code
InChI=1S/C44H28N4O12S4.ClH.Mn/c49-61(50,51)29-9-1-25(2-10-29)41-33-17-19-35(45-33)42(26-3-11-30(12-4-26)62(52,53)54)37-21-23-39(47-37)44(28-7-15-32(16-8-28)64(58,59)60)40-24-22-38(48-40)43(36-20-18-34(41)46-36)27-5-13-31(14-6-27)63(55,56)57;;/h1-24H,(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60);1H;/q-2;;+3/p-1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-;;
SMILES Code
Cl[Mn](N/12)N3C4=CC=C3/C(C5=CC=C(S(=O)(O)=O)C=C5)=C(C=C6)\N=C6/C(C7=CC=C(S(=O)(O)=O)C=C7)=C2/C=CC1=C(C(C=C/8)=NC8=C4\C9=CC=C(S(=O)(O)=O)C=C9)/C%10=CC=C(S(=O)(O)=O)C=C%10
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
1,023.35
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1.) Fiel, et al. Mechanism of the localization of manganese (III) mesotetra(4-sulfonatophenyl)porphine i in mice bearing L1210 tumors. Cancer Letters. Volume 40, Issue 1, May 1988, Pages 23-32. https://doi.org/10.1016/0304-3835(88)90258-3
2.) Schaefle, et al. NMR Paramagnetic Relaxation of the Spin 2 Complex MnIIITSPP: A Unique Mechanism. J. Phys. Chem. A 2005, 109, 15, 3267–3275. https://doi.org/10.1021/jp046227o
3.) Cheng, et al. Complementary Strategies for Developing Gd-Free High-Field T1 MRI Contrast Agents Based on MnIII Porphyrins. J. Med. Chem. 2014, 57, 2, 516–520. https://doi.org/10.1021/jm401124b
4.) Lu, et al. Manganese(III) porphyrin oligomers as high-relaxivity MRI contrast agents. Bioorganic & Medicinal Chemistry. Volume 35, 1 April 2021, 116090. https://doi.org/10.1016/j.bmc.2021.116090
5.) Wang, et al. Porphyrin-Based Honeycomb Films and Their Antibacterial Activity. Langmuir 2014, 30, 22, 6419–6426. https://doi.org/10.1021/la501244s
6.) Koposova EA, Offenhäusser A, Ermolenko YE and Mourzina YG (2019) Photoresponsive Porphyrin Nanotubes of Meso-tetra(4-Sulfonatophenyl)Porphyrin and Sn(IV) meso-tetra(4-pyridyl)porphyrin. Front. Chem.7:351. doi: 10.3389/fchem.2019.00351
