MedKoo Cat#: 563210 | Name: WWL229
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

WWL229 is a selective inhibitor of carboxylesterase 3 (Ces3) with an IC₅₀ of 1.94 µM. By inhibiting Ces3, WWL229 promotes lipid storage in cultured adipocytes and prevents basal lipolysis.

Chemical Structure

WWL229
WWL229
CAS#1338575-28-2

Theoretical Analysis

MedKoo Cat#: 563210

Name: WWL229

CAS#: 1338575-28-2

Chemical Formula: C16H22N2O5

Exact Mass: 322.1529

Molecular Weight: 322.36

Elemental Analysis: C, 59.62; H, 6.88; N, 8.69; O, 24.82

Price and Availability

Size Price Availability Quantity
25mg USD 250.00 2 Weeks
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,450.00 2 Weeks
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Related CAS #
No Data
Synonym
WWL229; WWL-229; WWL 229;
IUPAC/Chemical Name
4-Nitrophenyl 2-(3-methoxypropyl)piperidine-1-carboxylate
InChi Key
XVBRVSAGMWRVCK-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H22N2O5/c1-22-12-4-6-13-5-2-3-11-17(13)16(19)23-15-9-7-14(8-10-15)18(20)21/h7-10,13H,2-6,11-12H2,1H3
SMILES Code
O=C(N1C(CCCOC)CCCC1)OC2=CC=C([N+]([O-])=O)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 322.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Soni KG, Lehner R, Metalnikov P, O'Donnell P, Semache M, Gao W, Ashman K, Pshezhetsky AV, Mitchell GA. Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase. J Biol Chem. 2004 Sep 24;279(39):40683-9. Epub 2004 Jun 25. PubMed PMID: 15220344.