Dimethisterone | CAS# 79-64-1 | synthetic progestational hormone

MedKoo Cat#: 413763 | Name: Dimethisterone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dimethisterone is a synthetic progestational hormone without significant estrogenic or androgenic properties. It was formerly used as the progestational component in oral sequential contraceptives.

Chemical Structure

Dimethisterone

CAS#79-64-1

Theoretical Analysis

MedKoo Cat#: 413763

Name: Dimethisterone

CAS#: 79-64-1

Chemical Formula: C23H32O2

Exact Mass: 340.2402

Molecular Weight: 340.51

Elemental Analysis: C, 81.13; H, 9.47; O, 9.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Dimethisterone; P5048; P 5048; P-5048

IUPAC/Chemical Name

(6-alpha,17-beta)-17-Hydroxy-6-methyl-17-(1-propynyl)-androst-4-en-3-one

InChi Key

LVHOURKCKUYIGK-RGUJTQARSA-N

InChi Code

InChI=1S/C23H32O2/c1-5-9-23(25)12-8-19-17-13-15(2)20-14-16(24)6-10-21(20,3)18(17)7-11-22(19,23)4/h14-15,17-19,25H,6-8,10-13H2,1-4H3/t15-,17+,18-,19-,21+,22-,23-/m0/s1

SMILES Code

C[C@@]12[C@@](C#CC)(O)CC[C@@]1([H])[C@]3([H])C[C@H](C)C4=CC(CC[C@]4(C)[C@@]3([H])CC2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 340.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dimethisterone. Med Actual. 1968;4(1):7-9. PMID: 12255347. 2: Dimethisterone. IARC Monogr Eval Carcinog Risk Chem Hum. 1979 Dec;21:377-85. PMID: 296133. 3: Weikel JH Jr, Nelson LW. Problems in evaluating chronic toxicity of contraceptive steroids in dogs. J Toxicol Environ Health. 1977 Sep;3(1-2):167-77. doi: 10.1080/15287397709529556. PMID: 72828. 4: Majewski RF, Berdahl JM, Jost LD, Martin TA, Simms JC, Schmidt JG, Corrigan JR. Autoxidation of dimethisterone. Steroids. 1970 Jul;16(1):15-27. doi: 10.1016/s0039-128x(70)80092-7. PMID: 5471532. 5: Applezweig N. Steroids. Chem Week. 1969 May 17;104:57-72. PMID: 12255132. 6: Tyler ET. Antifertility agents. Annu Rev Pharmacol. 1967;7:381-98. doi: 10.1146/annurev.pa.07.040167.002121. PMID: 5337087. 7: AYDAR CK, GREENBLATT RB. Clinical and experimental studies with a new progestogen--dimethisterone. J Med Assoc State Ala. 1961 Sep;31:53-9. PMID: 13685370. 8: Morrison J, Blunt VA. Palliation of metastatic endometrial adenocarcinoma with dimethisterone. Aust N Z J Obstet Gynaecol. 1972 Feb;12(1):27-9. doi: 10.1111/j.1479-828x.1972.tb00724.x. PMID: 4112032. 9: Hayakawa K. Effects of dimethisterone on endometrial adenocarcinoma--electron microscopic study. Acta Obstet Gynaecol Jpn. 1969 Oct;16(4):285-300. PMID: 5394734. 10: DAVID A, FELLOWES KP, MILLSON DR. Some biological properties of dimethisterone "secrosteron" a new orally active progestational agent. J Pharm Pharmacol. 1959 Aug;11:491-5. doi: 10.1111/j.2042-7158.1959.tb12587.x. PMID: 13814263.