Dimecamine Free Base is a ganglion blocking agent. A slowly developing but moderate contracture of the chick biventer cervicis muscle was observed with 5x10-4M-dimecamine methiodide solution. A small reduction in the twitch response was also observed. Similar concentrations of dimecamine and pempidine produced only slowly developing and very small contractures. Dimecamine differs in neuromuscular-blocking activity from its corresponding quaternary metho-salts by a factor of less than two.
MedKoo Cat#: 413741
Name: Dimecamine Free Base
CAS#: 3570-07-8 (free base)
Chemical Formula: C12H23N
Exact Mass: 181.1830
Molecular Weight: 181.32
Elemental Analysis: C, 79.49; H, 12.79; N, 7.72
The following data is based on the product molecular weight 181.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
