MedKoo Cat#: 555966 | Name: AQX-016A
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AQX-016A, also known as NSC-741764, is a potent activator of SHIP-1.

Chemical Structure

AQX-016A
AQX-016A
CAS#849669-54-1

Theoretical Analysis

MedKoo Cat#: 555966

Name: AQX-016A

CAS#: 849669-54-1

Chemical Formula: C22H32O2

Exact Mass: 328.2402

Molecular Weight: 328.50

Elemental Analysis: C, 80.44; H, 9.82; O, 9.74

Price and Availability

Size Price Availability Quantity
50mg USD 1,650.00 2 Weeks
100mg USD 2,450.00 2 Weeks
200mg USD 3,450.00 2 Weeks
500mg USD 4,450.00 2 Weeks
1g USD 6,450.00 2 Weeks
2g USD 9,950.00 2 Weeks
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Related CAS #
No Data
Synonym
AQX-016A; AQX 016A; AQX016A; NSC-741764; NSC 741764; NSC741764;
IUPAC/Chemical Name
(6aR,11aR,11bS)-4,4,6a,7,11b-pentamethyl-1,2,3,4a,5,6,11,11a-octahydrobenzo[a]fluorene-9,10-diol
InChi Key
DTFQQAANPRPMBC-CZVICOMLSA-N
InChi Code
InChI=1S/C22H32O2/c1-13-11-15(23)19(24)14-12-17-21(4)9-6-8-20(2,3)16(21)7-10-22(17,5)18(13)14/h11,16-17,23-24H,6-10,12H2,1-5H3/t16?,17-,21+,22-/m1/s1
SMILES Code
OC1=C(O)C2=C(C(C)=C1)[C@]3(C)CCC(C(C)(C)CCC4)[C@@]4(C)[C@@]3([H])C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 328.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Ong CJ, Ming-Lum A, Nodwell M, Ghanipour A, Yang L, Williams DE, Kim J, Demirjian L, Qasimi P, Ruschmann J, Cao LP, Ma K, Chung SW, Duronio V, Andersen RJ, Krystal G, Mui AL. Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells. Blood. 2007 Sep 15;110(6):1942-9. doi: 10.1182/blood-2007-03-079699. Epub 2007 May 14. PMID: 17502453.