Dibenzepin (free base) | CAS# 4498-32-2 (free base) | tricyclic antidepressant

MedKoo Cat#: 413673 | Name: Dibenzepin (free base)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dibenzepin (free base) is a tricyclic antidepressant similar in action to imipramine.

Chemical Structure

Dibenzepin (free base)

CAS#4498-32-2 (free base)

Theoretical Analysis

MedKoo Cat#: 413673

Name: Dibenzepin (free base)

CAS#: 4498-32-2 (free base)

Chemical Formula: C18H21N3O

Exact Mass: 295.1685

Molecular Weight: 295.39

Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 73.19; H, 7.17; N, 14.23; O, 5.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

4498-32-2 (free base) 315-80-0 (HCl)

Synonym

Dibenzepin (free base); BRN0894708; BRN-0894708; BRN 0894708

IUPAC/Chemical Name

11H-Dibenzo(b,e)(1,4)diazepin-11-one, 10-(2-(dimethylamino)ethyl)-5,10-dihydro-5-methyl-

InChi Key

QPGGEKPRGVJKQB-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H21N3O/c1-19(2)12-13-21-17-11-7-6-10-16(17)20(3)15-9-5-4-8-14(15)18(21)22/h4-11H,12-13H2,1-3H3

SMILES Code

O=C1C2=CC=CC=C2N(C)C3=CC=CC=C3N1CCN(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 295.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gossweiler B. Vergiftungen mit Dibenzepin [Dibenzepin poisoning]. Schweiz Rundsch Med Prax. 1984 Feb 28;73(9):263-7. German. PMID: 6143381. 2: Gauch R, Modestin J. Zur Pharmakokinetik von Dibenzepin [Pharmacokinetics of dibenzepin]. Arzneimittelforschung. 1973 May;23(5):687-9. German. PMID: 4740212. 3: Rehavi M, Maayani S, Goldstein L, Assael M, Sokolovsky M. Antimuscarinic properties of antidepressants: dibenzepin (Noveril). Psychopharmacology (Berl). 1977 Aug 31;54(1):35-8. doi: 10.1007/BF00426538. PMID: 20647. 4: Ekdawi MY. Dibenzepin and amitriptyline in the treatment of depression. Br J Psychiatry. 1971 May;118(546):523-4. doi: 10.1192/bjp.118.546.523. PMID: 5580367. 5: McLinden VJ. Dibenzepin poisoning. J Forensic Sci Soc. 1970 Jul;10(3):135-8. doi: 10.1016/s0015-7368(70)70585-9. PMID: 5510629. 6: Baron DP, Unger HR, Williams HE, Knight RG. A double blind study of the antidepressants dibenzepin (Noveril) and amitriptyline. N Z Med J. 1976 Apr 28;83(562):273-4. PMID: 8749. 7: Noveril (dibenzepin)--another new antidepressive. Drug Ther Bull. 1970 Dec 18;8(26):103-4. PMID: 5492203. 8: Lingjaerde O. Dibenzepin (Deprex "Novo") [Dibenzepin (Deprex "Novo")]. Tidsskr Nor Laegeforen. 1968 Mar 1;88(5):342-3. Norwegian. PMID: 5671516. 9: Thorpe P, Marchant-Williams R. The role of an antidepressant, dibenzepin (Noveril), in the relief of pain in chronic arthritic states. Med J Aust. 1974 Feb 23;1(8):264-6. doi: 10.5694/j.1326-5377.1974.tb93144.x. PMID: 4595306. 10: Amitzur G, el-Sherif N, Gough WB. Electrophysiological effects of a chemical defibrillatory agent, dibenzepin. Cardiovasc Res. 1990 Oct;24(10):781-5. doi: 10.1093/cvr/24.10.781. PMID: 1982246.