MedKoo Cat#: 464356 | Name: D-HSL

Description:

WARNING: This product is for research use only, not for human or veterinary use.

D-homoserine lactone (D-HSL) is an enantiomer of L-homoserine lactone and an inhibitor of serine hydroxymethyltransferase (SHMT; Ki = 11 mM for the rabbit enzyme).

Chemical Structure

D-HSL
D-HSL
CAS#51744-82-2

Theoretical Analysis

MedKoo Cat#: 464356

Name: D-HSL

CAS#: 51744-82-2

Chemical Formula: C4H7NO2

Exact Mass: 101.0477

Molecular Weight: 101.11

Elemental Analysis: C, 47.52; H, 6.98; N, 13.85; O, 31.65

Price and Availability

Size Price Availability Quantity
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
D-HSL; D HSL; DHSL; D-Homoserine lactone; D Homoserine lactone;
IUPAC/Chemical Name
(R)-3-aminodihydrofuran-2(3H)-one
InChi Key
QJPWUUJVYOJNMH-GSVOUGTGSA-N
InChi Code
InChI=1S/C4H7NO2/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m1/s1
SMILES Code
N[C@H]1C(OCC1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 101.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shin D, Gorgulla C, Boursier ME, Rexrode N, Brown EC, Arthanari H, Blackwell HE, Nagarajan R. N-Acyl Homoserine Lactone Analog Modulators of the Pseudomonas aeruginosa Rhll Quorum Sensing Signal Synthase. ACS Chem Biol. 2019 Oct 18;14(10):2305-2314. doi: 10.1021/acschembio.9b00671. Epub 2019 Oct 9. PMID: 31545595; PMCID: PMC6948153.