MedKoo Cat#: 556206 | Name: UCB-9260
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UCB-9260 is an orally bioavailable TNF inhibitor. UCB-9260 inhibits TNF signalling by stabilising an asymmetric form of the trimer.

Chemical Structure

UCB-9260
UCB-9260
CAS#1515888-53-5

Theoretical Analysis

MedKoo Cat#: 556206

Name: UCB-9260

CAS#: 1515888-53-5

Chemical Formula: C26H25N5O

Exact Mass: 423.2059

Molecular Weight: 423.52

Elemental Analysis: C, 73.74; H, 5.95; N, 16.54; O, 3.78

Price and Availability

Size Price Availability Quantity
50mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
200mg USD 2,650.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
UCB-9260; UCB 9260; UCB9260;
IUPAC/Chemical Name
(1-(2,5-dimethylbenzyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-2-yl)(pyridin-4-yl)methanol
InChi Key
RZGFWGNCSYUEPR-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H25N5O/c1-17-4-5-18(2)21(12-17)16-31-24-13-20(22-14-28-30(3)15-22)6-7-23(24)29-26(31)25(32)19-8-10-27-11-9-19/h4-15,25,32H,16H2,1-3H3
SMILES Code
OC(C1=NC2=CC=C(C3=CN(C)N=C3)C=C2N1CC4=CC(C)=CC=C4C)C5=CC=NC=C5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 423.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
O'Connell J, Porter J, Kroeplien B, Norman T, Rapecki S, Davis R, McMillan D, Arakaki T, Burgin A, Fox Iii D, Ceska T, Lecomte F, Maloney A, Vugler A, Carrington B, Cossins BP, Bourne T, Lawson A. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795. doi: 10.1038/s41467-019-13616-1. PMID: 31857588; PMCID: PMC6923382.