Exp 063 | CAS# 153049-46-8 | partial β-agonist

MedKoo Cat#: 414184 | Name: Exp 063

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Exp 063 is a hybrid compound that possesses both the angiotensin II antagonist activity and the β-blocking activity. EXP 063 also acts as a partial β-agonist.

Chemical Structure

Exp 063

CAS#153049-46-8

Theoretical Analysis

MedKoo Cat#: 414184

Name: Exp 063

CAS#: 153049-46-8

Chemical Formula: C37H42N9O5

Exact Mass: 692.3309

Molecular Weight: 692.80

Elemental Analysis: C, 64.15; H, 6.11; N, 18.20; O, 11.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Exp 063; Exp063; Exp-063

IUPAC/Chemical Name

1H-Imidazole-5-carboxylic acid, 4-((((4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-1H-indol-2-yl)carbonyl)amino)methyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,2'-biphenyl)-4-yl)methyl)-

InChi Key

KCFOCMFYTXDUDN-UHFFFAOYSA-N

InChi Code

InChI=1S/C37H42N9O5/c1-4-9-32-41-30(20-39-34(48)29-18-27-28(40-29)10-8-11-31(27)51-22-26(47)19-38-23(2)3)33(35(49)50)46(32)21-24-12-14-25(15-13-24)37(16-6-5-7-17-37)36-42-44-45-43-36/h5-8,10-18,23,26,38,40,47H,4,9,19-22H2,1-3H3,(H,39,48)(H,49,50)(H,42,43,44,45)

SMILES Code

O=C(C1=C(CNC(C(N2)=CC3=C2C=CC=C3OCC(O)CNC(C)C)=O)N=C(CCC)N1CC4=CC=C(C5(C6=NN=NN6)=CC=CC=C5)C=C4)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 692.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wong PC, Duncia JV, Chiu AT, Olson RE, Rominger DH, Tam SW, Timmermans PB. EXP063, a nonpeptide angiotensin II and beta adrenergic receptor antagonist. J Pharmacol Exp Ther. 1993 Nov;267(2):641-7. PMID: 7902431.