MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 413574 | Name: Deslorelin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Deslorelin, sold under the brand names Ovuplant, SucroMate, and Suprelorin among others, is an injectable gonadotropin releasing hormone superagonist which is used in veterinary medicine for various indications.

Chemical Structure

Deslorelin
Deslorelin
CAS#57773-65-6 (free base)

Theoretical Analysis

MedKoo Cat#: 413574

Name: Deslorelin

CAS#: 57773-65-6 (free base)

Chemical Formula: C64H83N17O12

Exact Mass: 1281.6407

Molecular Weight: 1282.48

Elemental Analysis: C, 59.94; H, 6.52; N, 18.57; O, 14.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
57773-65-6 (free base) 82318-06-7 (acetate) 1642579-30-3
Synonym
Deslorelin; Ovuplant; SucroMate; Suprelorin; Tryptal; Desloreline; Deslorelinum; Somagard; D-Trp LHRH-PEA; Deslorelina
IUPAC/Chemical Name
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
InChi Key
GJKXGJCSJWBJEZ-XRSSZCMZSA-N
InChi Code
InChI=1S/C64H83N17O12/c1-4-68-62(92)53-16-10-24-81(53)63(93)46(15-9-23-69-64(65)66)74-56(86)47(25-35(2)3)75-58(88)49(27-37-30-70-43-13-7-5-11-41(37)43)77-57(87)48(26-36-17-19-40(83)20-18-36)76-61(91)52(33-82)80-59(89)50(28-38-31-71-44-14-8-6-12-42(38)44)78-60(90)51(29-39-32-67-34-72-39)79-55(85)45-21-22-54(84)73-45/h5-8,11-14,17-20,30-32,34-35,45-53,70-71,82-83H,4,9-10,15-16,21-29,33H2,1-3H3,(H,67,72)(H,68,92)(H,73,84)(H,74,86)(H,75,88)(H,76,91)(H,77,87)(H,78,90)(H,79,85)(H,80,89)(H4,65,66,69)/t45-,46-,47-,48-,49+,50-,51-,52-,53-/m0/s1
SMILES Code
CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,282.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bonacina E, Negri G, Mattiello S, Gabai G, Groppetti D. Deslorelin subcutaneous implants in Oryx dammah males for reproductive control. Theriogenology. 2020 Jun;149:72-78. doi: 10.1016/j.theriogenology.2020.03.018. Epub 2020 Mar 16. PMID: 32247215. 2: UCVM DVM Class of 2018, Kwong GPS, Klein C. Deslorelin and naltrexone stimulate follicular development in mares during autumn transition and early anestrus. Can Vet J. 2019 Aug;60(8):855-858. PMID: 31391602; PMCID: PMC6625173. 3: Fontaine C. Long-term contraception in a small implant: A review of Suprelorin (deslorelin) studies in cats. J Feline Med Surg. 2015 Sep;17(9):766-71. doi: 10.1177/1098612X15594990. PMID: 26323800; PMCID: PMC5117121. 4: Lucas X. Clinical use of deslorelin (GnRH agonist) in companion animals: a review. Reprod Domest Anim. 2014 Oct;49 Suppl 4:64-71. doi: 10.1111/rda.12388. PMID: 25277434. 5: Haen SM, Heinonen M, Kauffold J, Heikinheimo M, Hoving LL, Soede NM, Peltoniemi OAT. GnRH-agonist deslorelin implant alters the progesterone release pattern during early pregnancy in gilts. Reprod Domest Anim. 2019 Mar;54(3):464-472. doi: 10.1111/rda.13376. Epub 2019 Jan 11. PMID: 30431675. 6: Cowan ML, Martin GB, Monks DJ, Johnston SD, Doneley RJ, Blackberry MA. Inhibition of the reproductive system by deslorelin in male and female pigeons (Columba livia). J Avian Med Surg. 2014 Jun;28(2):102-8. doi: 10.1647/2013-027. PMID: 25115038. 7: Koushik K, Dhanda DS, Cheruvu NP, Kompella UB. Pulmonary delivery of deslorelin: large-porous PLGA particles and HPbetaCD complexes. Pharm Res. 2004 Jul;21(7):1119-26. doi: 10.1023/b:pham.0000032997.96823.88. PMID: 15290850. 8: Cowl VB, Walker SL, Rambaud YF. ASSESSING THE EFFICACY OF DESLORELIN ACETATE IMPLANTS (SUPRELORIN) IN ALTERNATIVE PLACEMENT SITES. J Zoo Wildl Med. 2018 Mar;49(1):1-8. doi: 10.1638/2017-0153R.1. PMID: 29517451. 9: Palm J, Reichler IM. Der Einsatz von Deslorelinazetat (Suprelorin®) in der Kleintiermedizin [The use of deslorelin acetate (Suprelorin®) in companion animal medicine]. Schweiz Arch Tierheilkd. 2012 Jan;154(1):7-12. German. doi: 10.1024/0036-7281/a000286. PMID: 22222897. 10: Martinez G, Lacoste R, Dumasy M, Garbit S, Brouillet S, Coutton C, Arnoult C, Druelle F, Molina-Vila P. Deslorelin acetate implant induces transient sterility and behavior changes in male olive baboon (Papio anubis): A case study. J Med Primatol. 2020 Dec;49(6):344-348. doi: 10.1111/jmp.12479. Epub 2020 Jun 10. PMID: 32524631.

View History

Nemorone

Nemorone