MedKoo Cat#: 578148 | Name: Nicotine tartrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nicotine tartrate is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.

Chemical Structure

Nicotine tartrate
CAS#3275-73-8

Theoretical Analysis

MedKoo Cat#: 578148

Name: Nicotine tartrate

CAS#: 3275-73-8

Chemical Formula: C14H20N2O6

Exact Mass: 312.1321

Molecular Weight: 312.32

Elemental Analysis: C, 53.84; H, 6.45; N, 8.97; O, 30.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Nicotine tartrate
IUPAC/Chemical Name
Pyridine, 3-((2S)-1-methyl-2-pyrrolidinyl)-, (2R,3R)-2,3-dihydroxybutanedioate
InChi Key
QLDPCHZQQIASHX-MSDAVRDESA-N
InChi Code
InChI=1S/C10H14N2.C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t10-;1-,2-/m00/s1
SMILES Code
CN1CCC[C@H]1c2cccnc2.O[C@@H]([C@H](O)C(=O)O)C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 312.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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SAGE Open Med. 2018 May 21;6:2050312118777953. doi: 10.1177/2050312118777953. eCollection 2018. PubMed PMID: 29844912; PubMed Central PMCID: PMC5966839. 8: Behar RZ, Luo W, McWhirter KJ, Pankow JF, Talbot P. Analytical and toxicological evaluation of flavor chemicals in electronic cigarette refill fluids. Sci Rep. 2018 May 29;8(1):8288. doi: 10.1038/s41598-018-25575-6. PubMed PMID: 29844439. 9: Do EK, Prom-Wormley EC, Fuemmeler BF, Dick DM, Kendler KS, Maes HH. Associations Between Initial Subjective Experiences with Tobacco and Self-Reported Recent Use in Young Adulthood. Subst Use Misuse. 2018 May 29:1-8. doi: 10.1080/10826084.2018.1473435. [Epub ahead of print] PubMed PMID: 29843549. 10: Michelogiannakis D, Rossouw PE, Al-Shammery D, Akram Z, Khan J, Romanos GE, Javed F. Influence of nicotine on orthodontic tooth movement: A systematic review of experimental studies in rats. Arch Oral Biol. 2018 May 23;93:66-73. doi: 10.1016/j.archoralbio.2018.05.016. [Epub ahead of print] Review. PubMed PMID: 29843070. 11: Tararina MA, Xue S, Smith LC, Muellers SN, Miranda PO, Janda KD, Allen KN. Crystallography Coupled with Kinetic Analysis Provide Mechanistic Underpinnings of a Nicotine-Degrading Enzyme. Biochemistry. 2018 May 29. doi: 10.1021/acs.biochem.8b00384. [Epub ahead of print] PubMed PMID: 29812904. 12: Buckell J, Marti J, Sindelar JL. Should flavours be banned in cigarettes and e-cigarettes? Evidence on adult smokers and recent quitters from a discrete choice experiment. Tob Control. 2018 May 28. pii: tobaccocontrol-2017-054165. doi: 10.1136/tobaccocontrol-2017-054165. [Epub ahead of print] PubMed PMID: 29807947. 13: Jawad M, Eissenberg T, Salman R, Soule E, Alzoubi KH, Khabour OF, Karaoghlanian N, Baalbaki R, El Hage R, Saliba NA, Shihadeh A. Toxicant inhalation among singleton waterpipe tobacco users in natural settings. Tob Control. 2018 May 28. pii: tobaccocontrol-2017-054230. doi: 10.1136/tobaccocontrol-2017-054230. [Epub ahead of print] PubMed PMID: 29807946. 14: Staal YC, van de Nobelen S, Havermans A, Talhout R. New Tobacco and Tobacco-Related Products: Early Detection of Product Development, Marketing Strategies, and Consumer Interest. JMIR Public Health Surveill. 2018 May 28;4(2):e55. doi: 10.2196/publichealth.7359. PubMed PMID: 29807884. 15: Dautzenberg B. [Understand the tobacco industry's strategy for recruiting teens: Lessons from a 1973 marketing document]. Rev Pneumol Clin. 2018 May 25. pii: S0761-8417(18)30102-0. doi: 10.1016/j.pneumo.2018.04.006. [Epub ahead of print] French. PubMed PMID: 29807733. 16: Chen YH, Lin BJ, Hsieh TH, Kuo TT, Miller J, Chou YC, Huang EY, Hoffer BJ. Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens. Cell Transplant. 2018 Jan 1:963689718775382. doi: 10.1177/0963689718775382. [Epub ahead of print] PubMed PMID: 29807460. 17: Stefanovics EA, Potenza MN, Pietrzak RH. The physical and mental health burden of obesity in U.S. veterans: Results from the National Health and Resilience in Veterans Study. J Psychiatr Res. 2018 May 22;103:112-119. doi: 10.1016/j.jpsychires.2018.05.016. [Epub ahead of print] PubMed PMID: 29807318. 18: Bisong SA, Ukoh IE, Nna VU, Ebong PE. Vitamin E attenuates nicotine- and noise-induced reproductive impairment in male albino Wistar rats. Andrologia. 2018 May 28:e13050. doi: 10.1111/and.13050. [Epub ahead of print] PubMed PMID: 29806220. 19: Kassem NOF, Kassem NO, Liles S, Jackson SR, Posis AIB, Chatfield DA, Hovell MF. Levels of Urine Cotinine from Hookah Smoking and Exposure to Hookah Tobacco Secondhand Smoke in Hookah Lounges and Homes. Int J High Risk Behav Addict. 2018 Mar;7(1). pii: e67601. doi: 10.5812/ijhrba.67601. Epub 2018 Feb 19. PubMed PMID: 29805963; PubMed Central PMCID: PMC5967845. 20: Nouri-Shirazi M, Tamjidi S, Nourishirazi E, Guinet E. Combination of TLR8 and TLR4 agonists reduces the degrading effects of nicotine on DC-NK mediated effector T cell generation. Int Immunopharmacol. 2018 May 24;61:54-63. doi: 10.1016/j.intimp.2018.05.012. [Epub ahead of print] PubMed PMID: 29803914.