Daledalin | CAS# 22136-27-2 (free base) | selective norepinephrine reuptake inhibitor

MedKoo Cat#: 413453 | Name: Daledalin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Daledalin is an antidepressant which was synthesized and trialed for depression in the early 1970s, but was never marketed. It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.

Chemical Structure

Daledalin

CAS#22136-27-2 (free base)

Theoretical Analysis

MedKoo Cat#: 413453

Name: Daledalin

CAS#: 22136-27-2 (free base)

Chemical Formula: C19H24N2

Exact Mass: 280.1939

Molecular Weight: 280.42

Elemental Analysis: C, 81.38; H, 8.63; N, 9.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

22136-27-2 (free base) 23226-37-1 (tosylate)

Synonym

Daledalin; UK3557; UK-3557; UK 3557

IUPAC/Chemical Name

1H-Indole-3-propanamine, 2,3-dihydro-N,3-dimethyl-1-phenyl-

InChi Key

YFAIJBZEDDOCAN-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H24N2/c1-19(13-8-14-20-2)15-21(16-9-4-3-5-10-16)18-12-7-6-11-17(18)19/h3-7,9-12,20H,8,13-15H2,1-2H3

SMILES Code

CC1(CCCNC)CN(C2=CC=CC=C2)C3=C1C=CC=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

to be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM	comments
Solubility
	To be determined	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 280.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Edwards JG, Ollerenshaw DP. Daledalin tosylate: a controlled trial in depressive illness. Curr Med Res Opin. 1974;2(6):305-12. PubMed PMID: 4614944.