Guamecycline 2HCl | CAS# 13040-98-7 | Biochemical

MedKoo Cat#: 576048 | Name: Guamecycline 2HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Guamecycline 2HCl is an antibiotic with antitumor activity.

Chemical Structure

Guamecycline 2HCl

CAS#13040-98-7

Theoretical Analysis

MedKoo Cat#: 576048

Name: Guamecycline 2HCl

CAS#: 13040-98-7

Chemical Formula: C29H40Cl2N8O8

Exact Mass: 698.2346

Molecular Weight: 699.59

Elemental Analysis: C, 49.79; H, 5.76; Cl, 10.13; N, 16.02; O, 18.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Guamecycline dihydrochloride; Guamecycline 2HCl; Xanthocycline; Xanthomycin

IUPAC/Chemical Name

2-Naphthacenecarboxamide, N-((4-(amidinoamidino)-1-piperazinyl)methyl)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, dihydrochloride

InChi Key

SNUNMHCZVZIEMV-KGHBUBBXSA-N

InChi Code

InChI=1S/C29H38N8O8.2ClH/c1-28(44)13-5-4-6-16(38)17(13)21(39)18-14(28)11-15-20(35(2)3)22(40)19(24(42)29(15,45)23(18)41)25(43)33-12-36-7-9-37(10-8-36)27(32)34-26(30)31;;/h4-6,14-15,20,38,40-41,44-45H,7-12H2,1-3H3,(H,33,43)(H5,30,31,32,34);2*1H/t14-,15-,20-,28+,29-;;/m0../s1

SMILES Code

Cl.Cl.CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)NCN4CCN(CC4)C(=N)NC(=N)N)C(=O)c5c(O)cccc5[C@@]3(C)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 699.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Logico G, Favero S, Piva A, Conz A. [Bacterial activity and salivary concentration of xanthocycline]. G Stomatol Ortognatodonzia. 1984 Oct-Dec;3(4):718-9. Italian. PubMed PMID: 6443215. 2: Nishimura T, Kitajima J, Omura S, Tanaka N. Antitumor activity of an antibiotic identical with or closely related to xanthomycin A. J Antibiot (Tokyo). 1981 Jul;34(7):856-61. PubMed PMID: 7287588. 3: Bocarnea C, Duminica A. [Guamecycline in the treatment of acute pneumopathies. Clinical research and comparison with other tetracyclines]. Minerva Med. 1972 Nov 21;63(83):4533-6. Italian. PubMed PMID: 4565314. 4: Lányi M, Hordós A, Major T, Tarján E, Zolnay E. Guamecycline in bronchial infections due to Diplococcus pneumoniae. Panminerva Med. 1972 Jan-Feb;14(1-2):24-9. PubMed PMID: 4156979. 5: Bottero A, Pellegrini R, Lops M. [Effects of aerosol administration of guamecycline in patients with broncho-pulmonary diseases]. Epatologia. 1971 Jan-Feb;17(1):85-95. Italian. PubMed PMID: 5147865.