Naamidine J | CAS# | Marine Natural

MedKoo Cat#: 123204 | Name: Naamidine J

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Naamidine J is a marine natural product.

Chemical Structure

Naamidine J

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 123204

Name: Naamidine J

CAS#: N/A

Chemical Formula: C25H27N5O5

Exact Mass: 477.2000

Molecular Weight: 477.52

Elemental Analysis: C, 62.88; H, 5.70; N, 14.67; O, 16.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Naamidine J; NaamidineJ; Naamidine-J; J3.538.400F

IUPAC/Chemical Name

4-((5-(3,4-dimethoxybenzyl)-4-(4-methoxybenzyl)-1-methyl-1H-imidazol-2-yl)amino)-1-methyl-1H-imidazole-2,5-dione

InChi Key

BNRNBQPXQALGJR-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H27N5O5/c1-29-19(13-16-8-11-20(34-4)21(14-16)35-5)18(12-15-6-9-17(33-3)10-7-15)26-24(29)27-22-23(31)30(2)25(32)28-22/h6-11,14H,12-13H2,1-5H3,(H,26,27,28,32)

SMILES Code

CN1C(CC2=CC(OC)=C(OC)C=C2)=C(CC3=CC=C(OC)C=C3)N=C1NC(C(N4C)=O)=NC4=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 477.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Fu PP, Wang Q, Zhang Q, Jin Y, Liu J, Chen KX, Guo YW, Liu SH, Li XW. Bioactivity-Driven Synthesis of the Marine Natural Product Naamidine J and Its Derivatives as Potential Tumor Immunological Agents by Inhibiting Programmed Death-Ligand 1. J Med Chem. 2023 Apr 11. doi: 10.1021/acs.jmedchem.2c01702. Epub ahead of print. PMID: 37040446. 2: Gong KK, Tang XL, Liu YS, Li PL, Li GQ. Imidazole Alkaloids from the South China Sea Sponge Pericharax heteroraphis and Their Cytotoxic and Antiviral Activities. Molecules. 2016 Jan 26;21(2):150. doi: 10.3390/molecules21020150. PMID: 26821008; PMCID: PMC6274532. 3: Tang WZ, Yang ZZ, Wu W, Tang J, Sun F, Wang SP, Cheng CW, Yang F, Lin HW. Imidazole Alkaloids and Their Zinc Complexes from the Calcareous Marine Sponge Leucetta chagosensis. J Nat Prod. 2018 Apr 27;81(4):894-900. doi: 10.1021/acs.jnatprod.7b01006. Epub 2018 Apr 12. PMID: 29648818. 4: An B, Yin F, de Voogd NJ, Chen X, Cheng W, Lin W. Chagosendines A - C, New Metal Complexes of Imidazole Alkaloids from the Calcareous Sponge Leucetta chagosensis. Chem Biodivers. 2018 Feb;15(2). doi: 10.1002/cbdv.201700481. Epub 2018 Jan 30. PMID: 29194948.