MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 585258 | Name: TS 88

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TS 88, also known as Menfegol, is a spermicide that suppresses sperm motility and kills sperm.

Chemical Structure

TS 88
TS 88
CAS#38193-77-0

Theoretical Analysis

MedKoo Cat#: 585258

Name: TS 88

CAS#: 38193-77-0

Chemical Formula: C18H28O2

Exact Mass: 276.2089

Molecular Weight: 276.42

Elemental Analysis: C, 78.21; H, 10.21; O, 11.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
TS 88; TS88; TS-88; Menfegol
IUPAC/Chemical Name
2-[4-(2-methyl-5-propan-2-ylcyclohexyl)phenoxy]ethanol
InChi Key
QNEAJARGVHIUBG-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H28O2/c1-13(2)16-5-4-14(3)18(12-16)15-6-8-17(9-7-15)20-11-10-19/h6-9,13-14,16,18-19H,4-5,10-12H2,1-3H3
SMILES Code
CC(C1CCC(C)C(C2=CC=C(OCCO)C=C2)C1)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 276.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Oshio S, Ozaki S, Ohkawa I, Tajima T, Tomomasa H, Amemiya H, Yazaki T, Mohri H, Umeda T. Spermicidal activity of menfegol-coated condom. Andrologia. 1990 May-Jun;22(3):291-6. PubMed PMID: 2240626. 2: Chompootaweep S, Dusitsin N. A comparative study of the safety, effectiveness and acceptability of two foaming vaginal tablets (nonoxynol-9 versus menfegol) in Thai women. Contraception. 1990 May;41(5):507-17. PubMed PMID: 2161308. 3: Oshio S, Tomomasa H, Amemiya H, Yazaki T, Umeda T, Mohri H, Ozaki S, Ohkawa I, Tajima T. [Effects of a condom coated with menfegol, a spermicide, on sperm motility and viability]. Nihon Funin Gakkai Zasshi. 1989 Oct;34(4):914-8. Japanese. PubMed PMID: 12158569. 4: Yamai S, Kuroki T, Watanabe Y, Takizawa K. In vitro effect of menfegol on Neisseria gonorrhoeae. Kansenshogaku Zasshi. 1989 Oct;63(10):1178-81. PubMed PMID: 2515225. 5: Goeman J, Ndoye I, Sakho LM, Mboup S, Piot P, Karam M, Belsey E, Lange JM, Laga M, Perriëns JH. Frequent use of menfegol spermicidal vaginal foaming tablets associated with a high incidence of genital lesions. J Infect Dis. 1995 Jun;171(6):1611-4. PubMed PMID: 7769301. 6: Chantler E, Fisher H, Solanki S, Elstein M. Quantification of the in vitro activity of some compounds with spermicidal activity. Contraception. 1992 Dec;46(6):527-36. PubMed PMID: 1283567. 7: Connell EB. Barrier contraceptives. Clin Obstet Gynecol. 1989 Jun;32(2):377-86. Review. PubMed PMID: 2663278. 8: Jones BM, Willcox LM. The susceptibility of organisms associated with bacterial vaginosis to spermicidal compounds, in vitro. Genitourin Med. 1991 Dec;67(6):475-7. PubMed PMID: 1774052; PubMed Central PMCID: PMC1194771. 9: Zaneveld LJ, Waller DP, Ahmad N, Quigg J, Kaminski J, Nikurs A, De Jonge C. Properties of a new, long-lasting vaginal delivery system (LASRS) for contraceptive and antimicrobial agents. J Androl. 2001 May-Jun;22(3):481-90. PubMed PMID: 11330649. 10: Jennings R, Clegg A. The inhibitory effect of spermicidal agents on replication of HSV-2 and HIV-1 in-vitro. J Antimicrob Chemother. 1993 Jul;32(1):71-82. PubMed PMID: 7693643. 11: Youssef H, Crofton VA, Smith SC, Siemens AJ. A clinical trial of Neo Sampoon vaginal tablets and Emko foam in Alexandria, Egypt. Contraception. 1987 Feb;35(2):101-10. PubMed PMID: 3297482. 12: Lamptey P, Klufio C, Smith SC, Feldblum PJ. A comparative study of Neo Sampoon, Ortho Vaginal Tablets and Emko Vaginal Tablets in Accra, Ghana. Contraception. 1985 Nov;32(5):445-54. PubMed PMID: 3002720. 13: Chi IC, Smith SC, Borko E, Sun TH, Begum SF, Hunt WL, Wilkens LR. Clinical acceptability, use-patterns and use-effectiveness of the vaginal contraceptive sponge and Neo Sampoon tablets--an international multi-center randomized clinical trial. Contraception. 1987 Nov;36(5):499-514. PubMed PMID: 3329078. 14: Furuse K, Ishizeki C, Iwahara S. Studies on spermicidal activity of surfactants. I. Correlation between spermicidal effect and physicochemical properties of p-menthanylphenyl polyoxyethylene (8.8) ether and related surfactants. J Pharmacobiodyn. 1983 Jun;6(6):359-72. PubMed PMID: 6631657. 15: Borko E, McIntyre SL, Feldblum PJ. A comparative clinical trial of the contraceptive sponge and Neo Sampoon tablets. Obstet Gynecol. 1985 Apr;65(4):511-5. PubMed PMID: 2984617. 16: Begum SF, Liao WC, McCann MF, Ahmad N. A clinical trial of Neo Sampoon vaginal contraceptive tablets. Contraception. 1980 Dec;22(6):573-82. PubMed PMID: 7214907. 17: Rosenberg M. Contraception and STDs. IPPF Med Bull. 1991 Oct;25(5):3-4. PubMed PMID: 12284650. 18: Berman SM. Fertility control and HIV infection. Arch AIDS Res. 1991;5(1-2):25-7. PubMed PMID: 12284239. 19: Edelman DA. The vaginal contraceptive sponge. IPPF Med Bull. 1984 Jun;18(3):1-2. PubMed PMID: 12266284. 20: Hong CY, Chiang BN, Ku J, Wei YH. Glutathione and caffeine antagonize the sperm-immobilizing effect of a vaginal contraceptive. Hum Toxicol. 1984 Aug;3(4):271-7. PubMed PMID: 6480005.

View History

UNC0006

UNC0006

Droloxifene

Droloxifene

DDD00079282

DDD00079282

Axinylsterol

Axinylsterol

Droprenilamine

Droprenilamine

AXT914

AXT914