Melicopine is an acridone alkaloid that has been found in Z. simulans and has antimalarial and anticancer activities. It is active against the chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum with IC50 values of 29.7 and 33.7 µg/ml, respectively. Melicopine is cytotoxic to PC-3M and LNCaP prostate cancer, but not non-cancerous HEK293, cells.
MedKoo Cat#: 464056
Name: Melicopine
CAS#: 568-01-4
Chemical Formula: C17H15NO5
Exact Mass: 313.0950
Molecular Weight: 313.31
Elemental Analysis: C, 65.17; H, 4.83; N, 4.47; O, 25.53
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| Soluble in DMSO | 0.0 | 100.00 |
The following data is based on the product molecular weight 313.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
