Synonym
Chloroserpidine; R616; R-616; R 616
IUPAC/Chemical Name
methyl (1S,2R,3R,4aS,13bR,14aS)-10-chloro-2-methoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
InChi Key
FQUMWACBNIURCJ-RWZVGCGMSA-N
InChi Code
InChI=1S/C32H37ClN2O8/c1-38-24-10-16(11-25(39-2)29(24)40-3)31(36)43-26-12-17-15-35-9-8-19-21-13-18(33)6-7-22(21)34-28(19)23(35)14-20(17)27(30(26)41-4)32(37)42-5/h6-7,10-11,13,17,20,23,26-27,30,34H,8-9,12,14-15H2,1-5H3/t17-,20+,23-,26-,27+,30+/m1/s1
SMILES Code
CO[C@H]1[C@H](OC(c2cc(OC)c(OC)c(OC)c2)=O)C[C@@H]3CN4CCc(c([C@H]4C[C@@H]3[C@@H]1C(OC)=O)[nH]5)c6c5ccc(Cl)c6
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
613.10
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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3: Hizay A, Seitz M, Grosheva M, Sinis N, Kaya Y, Bendella H, Sarikcioglu L, Dunlop SA, Angelov DN. FGF-2 is required to prevent astrogliosis in the facial nucleus after facial nerve injury and mechanical stimulation of denervated vibrissal muscles. J Biomed Res. 2016 Mar;30(2):142-148. doi: 10.7555/JBR.30.20140042. Epub 2016 Mar 20. PMID: 28276669; PMCID: PMC4820891.
4: Lindahl T. Fossil DNA. Curr Biol. 2000 Sep 7;10(17):R616. doi: 10.1016/s0960-9822(00)00668-0. PMID: 10996083.
5: Guo J, Zhou J, Wang D, Xiang X, Yu H, Tian C, Song Z. Correlation of anaerobic biodegradability and the electrochemical characteristic of azo dyes. Biodegradation. 2006 Aug;17(4):341-6. doi: 10.1007/s10532-005-9003-0. Epub 2005 Jul 23. PMID: 16819593.
