MedKoo Cat#: 413150 | Name: Clopipazan mesylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Clopipazan mesylate is an antipsychotic drug related to thioxanthenes. Quantitative pharmaco-EEG analyses showed systematic effects on human brain function with doses as low as 10 mg. In the early phase 2 clinical studies on chronic schizophrenic patients, however, the drug appeared to have a slow onset of action and weak neuroleptic potency.

Chemical Structure

Clopipazan mesylate
Clopipazan mesylate
CAS#60086-22-8 (mesylate)

Theoretical Analysis

MedKoo Cat#: 413150

Name: Clopipazan mesylate

CAS#: 60086-22-8 (mesylate)

Chemical Formula: C20H22ClNO4S

Exact Mass:

Molecular Weight: 407.91

Elemental Analysis: C, 58.89; H, 5.44; Cl, 8.69; N, 3.43; O, 15.69; S, 7.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Clopipazan mesylate; SKF69634; SKF-69634; SKF 69634
IUPAC/Chemical Name
Piperidine 4-(2-chloro-9H-xanthen-9-ylidene)-1-methyl-, methanesulfonate
InChi Key
CPNAKTVMAXLKKO-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H18ClNO.CH4O3S/c1-21-10-8-13(9-11-21)19-15-4-2-3-5-17(15)22-18-7-6-14(20)12-16(18)19;1-5(2,3)4/h2-7,12H,8-11H2,1H3;1H3,(H,2,3,4)
SMILES Code
CN1CC/C(CC1)=C2C3=C(OC4=C\2C=CC=C4)C=CC(Cl)=C3.CS(=O)(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 407.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same 'core' fraction of GABA(A) receptors