GR-63178A | CAS# 114517-04-3 | Biochemical

MedKoo Cat#: 575981 | Name: GR-63178A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GR-63178A is a novel pentacyclic pyrolloquinone anticancer drug.

Chemical Structure

GR-63178A

CAS#114517-04-3

Theoretical Analysis

MedKoo Cat#: 575981

Name: GR-63178A

CAS#: 114517-04-3

Chemical Formula: C28H22NO6P

Exact Mass: 499.1185

Molecular Weight: 499.46

Elemental Analysis: C, 67.33; H, 4.44; N, 2.80; O, 19.22; P, 6.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

GR63178A; GR 63178A; GR-63178A

IUPAC/Chemical Name

benzyl (14-methyl-8,13-dioxo-5,8,13,14-tetrahydrobenzo[5,6]isoindolo[2,1-b]isoquinolin-9-yl) hydrogen phosphate

InChi Key

UXTSQCOOUJTIAC-UHFFFAOYSA-N

InChi Code

InChI=1S/C28H22NO6P/c1-17-20-11-6-5-10-19(20)14-29-15-22-25(26(17)29)27(30)21-12-7-13-23(24(21)28(22)31)35-36(32,33)34-16-18-8-3-2-4-9-18/h2-13,15,17H,14,16H2,1H3,(H,32,33)

SMILES Code

CC1c2ccccc2Cn3cc4C(=O)c5c(OP(=O)(O)OCc6ccccc6)cccc5C(=O)c4c13

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 499.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Cummings J, Graham MA, Hoey BM, Butler J, Fry AM, Hickson ID, Leonard G, French R, Smyth JF. Studies on the molecular pharmacology of GR63178A. A novel pentacyclic pyrolloquinone anticancer drug. Biochem Pharmacol. 1992 Aug 4;44(3):433-9. doi: 10.1016/0006-2952(92)90433-j. PMID: 1324674.