Synonym
Histamine phosphate; Histamine acid phosphate; Histamine biphosphate; Histamine diphosphate; Histamine dihydrogen phosphate;
IUPAC/Chemical Name
2-(1H-imidazol-4-yl)ethan-1-amine bis(phosphate)
InChi Key
ZHIBQGJKHVBLJJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C5H9N3.2H3O4P/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4)
SMILES Code
NCCC1=CNC=N1.OP(O)(O)=O.OP(O)(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
307.14
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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7: Simons FE, Simons KJ. Levocetirizine: pharmacokinetics and pharmacodynamics in children age 6 to 11 years. J Allergy Clin Immunol. 2005 Aug;116(2):355-61. doi: 10.1016/j.jaci.2005.04.010. PMID: 16083790.
8: Nett CS, Hosgood G, Heatley JJ, Foil CS, Tully TN Jr. Evaluation of intravenous fluorescein in intradermal allergy testing in psittacines. Vet Dermatol. 2003 Dec;14(6):323-32. doi: 10.1111/j.1365-3164.2003.00348.x. PMID: 14678444.
9: Larivée Y, Leon Z, Salas-Prato M, Ganeva E, Desrosiers M. Evaluation of the nasal response to histamine provocation with acoustic rhinometry. J Otolaryngol. 2001 Dec;30(6):319-23. doi: 10.2310/7070.2001.19350. PMID: 11771000.
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