Cefadroxil-d4 trifluoroacetate salt | CAS#1426215-61-3 | Cefadroxil quantification internal standard

MedKoo Cat#: 463926 | Name: Cefadroxil-d4 trifluoroacetate salt

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cefadroxil-d4 is intended for use as an internal standard for the quantification of cefadroxil by GC- or LC-MS. Cefadroxil is a semisynthetic cephalosporin antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria, including B. anthracis, V. cholerae, and P. multocida strains, among others. Cefadroxil is protective against infection by strains of S. pyogenes, S. pneumoniae, or S. aureus in mice with 50% protective dose (PD50) values of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.

Chemical Structure

Cefadroxil-d4 trifluoroacetate salt

CAS#1426215-61-3 (trifluoroacetate salt)

Theoretical Analysis

MedKoo Cat#: 463926

Name: Cefadroxil-d4 trifluoroacetate salt

CAS#: 1426215-61-3 (trifluoroacetate salt)

Chemical Formula: C18H14D4F3N3O7S

Exact Mass:

Molecular Weight: 481.44

Elemental Analysis: C, 44.91; H, 4.60; F, 11.84; N, 8.73; O, 23.26; S, 6.66

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Synonym

Cefadroxil-d4 trifluoroacetate salt; Cefadroxil d4 trifluoroacetate salt;

IUPAC/Chemical Name

(6S,7S)-7-((S)-2-amino-2-(4-hydroxyphenyl-2,3,5,6-d4)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compound with 2,2,2-trifluoroacetic acid (1:1)

InChi Key

PQRAWSCYCASBIK-ZUMXZNHYSA-N

InChi Code

InChI=1S/C16H17N3O5S.C2HF3O2/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;3-2(4,5)1(6)7/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);(H,6,7)/t10-,11-,15-;/m0./s1/i2D,3D,4D,5D;

SMILES Code

OC1=C(C([2H])=C(C([2H])=C1[2H])[C@@H](C(N[C@H]2C(N3[C@]2(SCC(C)=C3C(O)=O)[H])=O)=O)N)[2H].OC(C(F)(F)F)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 481.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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