Pomalidomide-PEG3-NH2 HCl, an important component in the synthesis of protein degraders, consists of a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with a pendant amine that reacts with the carboxyl group on the target ligand.
MedKoo Cat#: 130374
Name: Pomalidomide-PEG3-NH2 HCl
CAS#: N/A
Chemical Formula: C21H27ClN4O8
Exact Mass: 498.1517
Molecular Weight: 498.92
Elemental Analysis: C, 50.56; H, 5.46; Cl, 7.11; N, 11.23; O, 25.65
The following data is based on the product molecular weight 498.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
