Cyprolidol | CAS# 4904-00-1 (free base)| Antidepressant

MedKoo Cat#: 412929 | Name: Cyprolidol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cyprolidol is an antidepressant

Chemical Structure

Cyprolidol

CAS#4904-00-1 (free base)

Theoretical Analysis

MedKoo Cat#: 412929

Name: Cyprolidol

CAS#: 4904-00-1 (free base)

Chemical Formula: C21H19NO

Exact Mass: 301.1467

Molecular Weight: 301.39

Elemental Analysis: C, 83.69; H, 6.35; N, 4.65; O, 5.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

2364-72-9 (HCl) 4904-00-1 (free base)

Synonym

Cyprolidol; Cyprolidolum; UNII-321552050N

IUPAC/Chemical Name

Methanol, diphenyl(2-(4-pyridyl)cyclopropyl)-, (E)-

InChi Key

KPUSUIKQQCFQCX-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H19NO/c23-21(17-7-3-1-4-8-17,18-9-5-2-6-10-18)20-15-19(20)16-11-13-22-14-12-16/h1-14,19-20,23H,15H2

SMILES Code

OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3C(C4=CC=NC=C4)C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 301.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hekimian LJ, Gershon S, Floyd A. Cyprolidol and imipramine: a double-blind controlled study in endogenous depression. Arzneimittelforschung. 1969 Jun;19(6):955-6. PMID: 4896165. 2: Korol B, Brown ML, Sletten IW. Effects of a new antidepressant cyprolidol (IN-1060) upon the blood pressure responses to autonomic drugs in conscious dogs. Curr Ther Res Clin Exp. 1966 Nov;8(11):543-8. PMID: 4963159. 3: Brown ML, Gershon S, Korol B. Some pharmacological effects of a new potential antidepressant cyprolidol (IN-1060) compared with imipramine. Med Pharmacol Exp Int J Exp Med. 1966;15(4):329-43. doi: 10.1159/000135886. PMID: 6012765. 4: Miller L, Napoli M, O'Dell TB. Pharmacological evaluation of a potential psychotherapeutic agent: cyprolidol, a pyridylcyclopropane derivative. Arch Int Pharmacodyn Ther. 1967 Apr;166(2):313-23. PMID: 4963240.