MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 575602 | Name: Esomeprazole strontium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Esomeprazole strontium anhydrous is a biochemical with gastric proton pump inhibitor activity.

Chemical Structure

Esomeprazole strontium
Esomeprazole strontium
CAS#914613-86-8 (strontium)

Theoretical Analysis

MedKoo Cat#: 575602

Name: Esomeprazole strontium

CAS#: 914613-86-8 (strontium)

Chemical Formula: C34H36N6O6S2Sr

Exact Mass: 0.0000

Molecular Weight: 776.44

Elemental Analysis: C, 52.60; H, 4.67; N, 10.82; O, 12.36; S, 8.26; Sr, 11.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
161796-78-7 (sodium) 119141-88-7 (free base) 161973-10-0 (magnesium) 217087-09-7 (magnesium hydrate) 161796-84-5 (potassium) 914613-86-8 (strontium) 934714-36-0 (strontium hydrate)
Synonym
Esomeprazole strontium anhydrous; Fm0F67 anhydrous; Fm-0F67 anhydrous; Fm 0F67 anhydrous
IUPAC/Chemical Name
strontium (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
InChi Key
FEVPVZSYBDUVGY-YPPDDXJESA-N
InChi Code
InChI=1S/2C17H18N3O3S.Sr/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2/t2*24-;/m00./s1
SMILES Code
CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Sr+2]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 776.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lotfy HM, Amer SM, Zaazaa HE, Mostafa NS. A comparative study of the novel spectrophotometric methods versus conventional ones for the simultaneous determination of Esomeprazole magnesium trihydrate and Naproxen in their binary mixture. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Dec 5;151:538-46. doi: 10.1016/j.saa.2015.07.007. Epub 2015 Jul 3. PubMed PMID: 26162342. 2: Kan SL, Lu J, Liu JP, Zhao Y. Preparation and in vitro/in vivo evaluation of esomeprazole magnesium-modified release pellets. Drug Deliv. 2015 Jul 21:1-8. [Epub ahead of print] PubMed PMID: 24892629. 3: Kumar P, Ganure AL, Subudhi BB, Shukla S. Preparation and characterization of pH-sensitive methyl methacrylate-g-starch/hydroxypropylated starch hydrogels: in vitro and in vivo study on release of esomeprazole magnesium. Drug Deliv Transl Res. 2015 Jun;5(3):243-56. doi: 10.1007/s13346-015-0221-7. PubMed PMID: 25787732. 4: Liu Z, Wang W, Chen H, Liu J, Zhang W. Novel application method of talcum powder to prevent sticking tendency and modify release of esomeprazole magnesium enteric-coated pellets. Pharm Dev Technol. 2015 Feb 24:1-10. [Epub ahead of print] PubMed PMID: 25708151. 5: Choi Y, Han H, Shin D, Lim KS, Yu KS. Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers. Drug Des Devel Ther. 2015 Jul 31;9:4127-35. doi: 10.2147/DDDT.S86725. eCollection 2015. PubMed PMID: 26257511; PubMed Central PMCID: PMC4527374.