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MedKoo Cat#: 575562 | Name: Flurbiprofen sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Flurbiprofen sodium is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting carbonic anhydrase.

Chemical Structure

Flurbiprofen sodium
Flurbiprofen sodium
CAS#56767-76-1 (sodium)

Theoretical Analysis

MedKoo Cat#: 575562

Name: Flurbiprofen sodium

CAS#: 56767-76-1 (sodium)

Chemical Formula: C15H12FNaO2

Exact Mass: 266.0719

Molecular Weight: 266.25

Elemental Analysis: C, 67.67; H, 4.54; F, 7.14; Na, 8.63; O, 12.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
5104-49-4 (free acid) 56767-76-1 (sodium)
Synonym
Flurbiprofen sodium; Sodium flurbiprofen; Flurbiprofen sodium salt; Ocufen;
IUPAC/Chemical Name
(1,1'-Biphenyl)-4-acetic acid, 2-fluoro-alpha-methyl-, sodium salt
InChi Key
AUAGTGKMTMVIKN-UHFFFAOYSA-M
InChi Code
InChI=1S/C15H13FO2.Na/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11;/h2-10H,1H3,(H,17,18);/q;+1/p-1
SMILES Code
O=C([O-])C(C)C1=CC=C(C2=CC=CC=C2)C(F)=C1.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 266.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang L, Zhu J, Xu L, Zhang X, Wang H, Luo Z, Zhao Y, Yu Y, Zhang Y, Shi H, Bao H. Efficacy and safety of flurbiprofen axetil in the prevention of pain on propofol injection: a systematic review and meta-analysis. Med Sci Monit. 2014 Jun 17;20:995-1002. doi: 10.12659/MSM.890102. Review. PubMed PMID: 24935068; PubMed Central PMCID: PMC4070992. 2: Abdel-Aziz AA, Al-Badr AA, Hafez GA. Flurbiprofen. Profiles Drug Subst Excip Relat Methodol. 2012;37:113-81. doi: 10.1016/B978-0-12-397220-0.00004-0. Epub 2012 Mar 19. Review. PubMed PMID: 22469318. 3: Sultan A, McQuay HJ, Moore RA, Derry S. Single dose oral flurbiprofen for acute postoperative pain in adults. Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007358. doi: 10.1002/14651858.CD007358.pub2. Review. PubMed PMID: 19588427; PubMed Central PMCID: PMC4164829. 4: Geerts H. Drug evaluation: (R)-flurbiprofen--an enantiomer of flurbiprofen for the treatment of Alzheimer's disease. IDrugs. 2007 Feb;10(2):121-33. Review. PubMed PMID: 17285465. 5: Romano A, Pietrantonio F. Delayed hypersensitivity to flurbiprofen. J Intern Med. 1997 Jan;241(1):81-3. Review. PubMed PMID: 9042097.