MedKoo Cat#: 412748 | Name: CGS 13928C

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CGS 13928C is a potent converting enzyme inhibitor

Chemical Structure

CGS 13928C
CGS 13928C
CAS#83348-78-1

Theoretical Analysis

MedKoo Cat#: 412748

Name: CGS 13928C

CAS#: 83348-78-1

Chemical Formula: C24H27N2NaO5

Exact Mass: 446.1818

Molecular Weight: 446.48

Elemental Analysis: C, 64.56; H, 6.10; N, 6.27; Na, 5.15; O, 17.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
CGS 13928C, CGS13928C, CGS 13928C
IUPAC/Chemical Name
sodium (S)-1-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)indoline-2-carboxylate
InChi Key
XPOXELABJLPBTQ-FMCJTSGUSA-M
InChi Code
InChI=1S/C24H28N2O5.Na/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29;/h4-12,16,19,21,25H,3,13-15H2,1-2H3,(H,28,29);/q;+1/p-1/t16-,19-,21-;/m0./s1
SMILES Code
CCOC([C@@H](N[C@H](C(N1[C@H](C([O-])=O)Cc2c1cccc2)=O)C)CCc3ccccc3)=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 446.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Brunner HR, Nussberger J, Waeber B. The present molecules of converting enzyme inhibitors. J Cardiovasc Pharmacol. 1985;7 Suppl 1:S2-11. doi: 10.1097/00005344-198507001-00002. PMID: 2580170. 2: Schaller MD, Brunner DB, Nussberger J, Turini GA, Sen SB, Chen D, Waeber B, Brunner HR. A potent converting enzyme inhibitor CGS 13928C. Drug profile in normal volunteers. Eur J Clin Pharmacol. 1984;26(4):419-24. doi: 10.1007/BF00542134. PMID: 6329767. 3: Capdeville C, el Bouhtoury F, Parache RM, Boulu RG, Guillou J, Atkinson J. The angiotensin I converting enzyme inhibitors, captopril and Wy-44,655 attenuate the consequences of cerebral ischemia in renovascular hypertensive rats. Life Sci. 1990;47(6):539-46. doi: 10.1016/0024-3205(90)90614-w. PMID: 2205771.