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MedKoo Cat#: 463593 | Name: EG 1088

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EG 1088 is a biochemical used in studies with stroke-prone spontaneously hypertensive rats.

Chemical Structure

EG 1088
EG 1088
CAS#82163-55-1

Theoretical Analysis

MedKoo Cat#: 463593

Name: EG 1088

CAS#: 82163-55-1

Chemical Formula: C22H22ClN3O5

Exact Mass: 443.1248

Molecular Weight: 443.88

Elemental Analysis: C, 59.53; H, 5.00; Cl, 7.99; N, 9.47; O, 18.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
EG 1088; EG1088; EG-1088;
IUPAC/Chemical Name
ethyl 3-(2-chlorophenyl)-5,7-dimethyl-2-(((methylcarbamoyl)oxy)methyl)-4-oxo-3,4-dihydroquinazoline-6-carboxylate
InChi Key
NUVXJFLCRWIOHW-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H22ClN3O5/c1-5-30-21(28)18-12(2)10-15-19(13(18)3)20(27)26(16-9-7-6-8-14(16)23)17(25-15)11-31-22(29)24-4/h6-10H,5,11H2,1-4H3,(H,24,29)
SMILES Code
CCOC(c1c(C)c2c(N=C(N(c3c(Cl)cccc3)C2=O)COC(NC)=O)cc1C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 443.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kobayashi M, Moriya K, Eguchi Y, Sugimoto A, Ito S, Ishikawa M. [Effect of EG-1088, EG-626 and nifedipine on vascular lesions associated with hypertension and hyperlipidemia in stroke-prone spontaneously hypertensive rats (SHR-SP)]. Tokyo Ika Shika Daigaku Iyo Kizai Kenkyusho Hokoku. 1984;18:25-38. Japanese. PMID: 6598494. 2: Kobayashi M, Moriya K, Eguchi Y, Sugimoto A, Ito S, Ishikawa M. [Preventive effect of EG-1088 on cholesterol infiltration into the aortic wall, and plasma lipid of long-term high fat-cholesterol feeding in stroke-prone (SHR) rats]. Tokyo Ika Shika Daigaku Iyo Kizai Kenkyusho Hokoku. 1983;17:57-64. Japanese. PMID: 6588435. 3: Kobayashi M, Moriya K, Eguchi Y, Sugimoto A, Ito S, Ishikawa M. [Prophylactic effect of EG-1088 on cerebrovascular lesions of stroke-prone spontaneously hypertensive rats]. Tokyo Ika Shika Daigaku Iyo Kizai Kenkyusho Hokoku. 1982;16:55-68. Japanese. PMID: 6964438.