MedKoo Cat#: 124743 | Name: Eg5-IN-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Eg5-IN-1 (compound 6c) is a potent kinesin family motor protein (Eg5) inhibitor

Chemical Structure

Eg5-IN-1
Eg5-IN-1
CAS#3026790-10-0

Theoretical Analysis

MedKoo Cat#: 124743

Name: Eg5-IN-1

CAS#: 3026790-10-0

Chemical Formula: C23H16ClFN4O

Exact Mass: 418.0997

Molecular Weight: 418.86

Elemental Analysis: C, 65.95; H, 3.85; Cl, 8.46; F, 4.54; N, 13.38; O, 3.82

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 5,650.00 2 Weeks
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Related CAS #
No Data
Synonym
Eg5-IN-1 ; Eg5 IN-1 ; Eg5-IN 1
IUPAC/Chemical Name
(E)-4-((7-chloroquinolin-4-yl)amino)-N'-(4-fluorobenzylidene)benzohydrazide
InChi Key
QZNZOQDFKRZJOE-MZJWZYIUSA-N
InChi Code
InChI=1S/C23H16ClFN4O/c24-17-5-10-20-21(11-12-26-22(20)13-17)28-19-8-3-16(4-9-19)23(30)29-27-14-15-1-6-18(25)7-2-15/h1-14H,(H,26,28)(H,29,30)/b27-14+
SMILES Code
ClC1=CC=C2C(N=CC=C2NC3=CC=C(C(N/N=C/C4=CC=C(F)C=C4)=O)C=C3)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 418.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Ranade SD, Alegaon SG, Venkatasubramanian U, Soundarya Priya A, Kavalapure RS, Chand J, Jalalpure SS, Vinod D. Design, synthesis, molecular dynamics simulation, MM/GBSA studies and kinesin spindle protein inhibitory evaluation of some 4-aminoquinoline hybrids. Comput Biol Chem. 2023 Aug;105:107881. doi: 10.1016/j.compbiolchem.2023.107881. Epub 2023 May 16. PMID: 37257398.