Synonym
4A-MPLA; Monophosphoryl Tetra-acyl Lipid A
IUPAC/Chemical Name
ammonium (2R,3S,4R,5R,6R)-6-(((2R,3S,4R,5R,6S)-3,6-dihydroxy-5-((R)-3-hydroxytetradecanamido)-4-(((R)-3-hydroxytetradecanoyl)oxy)tetrahydro-2H-pyran-2-yl)methoxy)-4-hydroxy-2-(hydroxymethyl)-5-((R)-3-(tetradecanoyloxy)tetradecanamido)tetrahydro-2H-pyran-3-yl hydrogen phosphate
InChi Key
KREAPURBNFKEHO-BNSRHSNQSA-N
InChi Code
InChI=1S/C68H129N2O19P.H3N/c1-5-9-13-17-21-25-26-30-34-38-42-46-59(76)85-54(45-41-37-33-29-24-20-16-12-8-4)49-58(75)69-61-64(79)65(89-90(81,82)83)55(50-71)87-68(61)84-51-56-63(78)66(88-60(77)48-53(73)44-40-36-32-28-23-19-15-11-7-3)62(67(80)86-56)70-57(74)47-52(72)43-39-35-31-27-22-18-14-10-6-2;/h52-56,61-68,71-73,78-80H,5-51H2,1-4H3,(H,69,75)(H,70,74)(H2,81,82,83);1H3/t52-,53-,54-,55-,56-,61-,62-,63-,64-,65-,66-,67+,68-;/m1./s1
SMILES Code
O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO)[C@@H](OP([O-])(O)=O)[C@@H]1O)O[C@H](O)[C@@H]2NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H]2OC(C[C@H](O)CCCCCCCCCCC)=O.[NH4+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
