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MedKoo Cat#: 412642 | Name: Cgp 20308

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cgp 20308 is a biochemical with antifilarial activity

Chemical Structure

Cgp 20308
Cgp 20308
CAS#74819-75-3

Theoretical Analysis

MedKoo Cat#: 412642

Name: Cgp 20308

CAS#: 74819-75-3

Chemical Formula: C13H14N2OS2

Exact Mass: 278.0548

Molecular Weight: 278.39

Elemental Analysis: C, 56.09; H, 5.07; N, 10.06; O, 5.75; S, 23.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Cgp 20308; Cgp20308; Cgp-20308
IUPAC/Chemical Name
Benzothiazole, 2-(1,1-dimethylethyl)-6-isothiocyanato-5-methoxy-
InChi Key
RLSTWBDBLBQLRC-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H14N2OS2/c1-13(2,3)12-15-9-5-10(16-4)8(14-7-17)6-11(9)18-12/h5-6H,1-4H3
SMILES Code
COC1=C(N=C=S)C=C(SC(C(C)(C)C)=N2)C2=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 278.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zahner H, Striebel HP, Sänger I, Schütze HR. Antifilarial activities of benzazole derivatives. 3. Effects of benzothiazoles on third stage larvae and preadult worms of Acanthocheilonema viteae, Brugia malayi and B. pahangi in Mastomys natalensis. Trop Med Parasitol. 1990 Dec;41(4):407-10. PMID: 2075385. 2: Franz M, Zahner H, Striebel HP, Langenstrassen L. Morphological alterations in female litomosoides carinii after treatment with two benzthiazole derivatives in vivo. Trop Med Parasitol. 1987 Mar;38(1):1-7. PMID: 3602833. 3: Zahner H, Striebel HP, Schütze HR, Sänger I, Müller HA, Schultheiss K. Antifilarial activities of benzazole derivatives. 2. Microfilaricidal effects against Litomosoides carinii, Acanthocheilonema. vitae, Brugia malayi and B. pahangi in Mastomys natalensis. Trop Med Parasitol. 1988 Dec;39(4):284-90. PMID: 3227232. 4: Davies KP, Zahner H, Köhler P. Litomosoides carinii: mode of action in vitro of benzothiazole and amoscanate derivatives with antifilarial activity. Exp Parasitol. 1989 May;68(4):382-91. doi: 10.1016/0014-4894(89)90123-9. PMID: 2721632.