Cgp 13231 | CAS#113962-61-1

MedKoo Cat#: 524614 | Name: Cgp 13231

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cgp 13231 is the N-oxide metabolite of amocarzine, CGP 6140.

Chemical Structure

Cgp 13231

CAS#113962-61-1

Theoretical Analysis

MedKoo Cat#: 524614

Name: Cgp 13231

CAS#: 113962-61-1

Chemical Formula: C18H21N5O3S

Exact Mass:

Molecular Weight: 387.46

Elemental Analysis: C, 55.80; H, 5.46; N, 18.08; O, 12.39; S, 8.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Cgp 13231; Cgp13231; Cgp-13231.

IUPAC/Chemical Name

1-Piperazinecarbothioamide, 4-methyl-N-(4-((4-nitrophenyl)amino)phenyl)-, 4-oxide

InChi Key

JSGITMPYGNUQPT-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H21N5O3S/c1-23(26)12-10-21(11-13-23)18(27)20-16-4-2-14(3-5-16)19-15-6-8-17(9-7-15)22(24)25/h2-9,19H,10-13H2,1H3,(H,20,27)

SMILES Code

C[N+]1(CCN(CC1)C(=S)Nc2ccc(cc2)Nc3ccc(cc3)[N+](=O)[O-])[O-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 387.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lecaillon JB, Poltera AA, Zea-Flores G, de Ramirez I, Nowell de Arevalo A. Influence of food related to dose on the pharmacokinetics of amocarzine and of its N-oxide metabolite, CGP 13 231, after oral administration to 20 onchocerciasis male patients from Guatemala. Trop Med Parasitol. 1991 Sep;42(3):286-90. PubMed PMID: 1801154. 2: Lecaillon JB, Dubois JP, Soula G, Pichard E, Poltera AA, Ginger CD. The influence of food on the pharmacokinetics of CGP 6140 (amocarzine) after oral administration of a 1200 mg single dose to patients with onchocerciasis. Br J Clin Pharmacol. 1990 Oct;30(4):629-33. PubMed PMID: 2291877; PubMed Central PMCID: PMC1368257.