VNN40497, also known as 1,2-dioleoyl-sn-glycero-3-succinate and 1,2-DOSG, is a useful lipid agent to make pH-sensitive liposomes for drug delivery, DNA, RNA, gene and vaccine delivery. VNN40497 was first reported in Biochimica et Biophysica Acta, Biomembranes (1990), 1025, (2), 234-42. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 555893
Name: VNN40497
CAS#: 127640-49-7 (R-isomer),
Chemical Formula: C43H76O8
Exact Mass: 720.5540
Molecular Weight: 721.07
Elemental Analysis: C, 71.63; H, 10.62; O, 17.75
The following data is based on the product molecular weight 721.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
