AZD-1175 | CAS# 863639-43-4 | Biochemical

MedKoo Cat#: 575195 | Name: AZD-1175

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZD-1175 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes and obesity.

Chemical Structure

AZD-1175

CAS#863639-43-4

Theoretical Analysis

MedKoo Cat#: 575195

Name: AZD-1175

CAS#: 863639-43-4

Chemical Formula: C25H25Cl2F3N4O4S

Exact Mass: 604.0926

Molecular Weight: 605.45

Elemental Analysis: C, 49.59; H, 4.16; Cl, 11.71; F, 9.41; N, 9.25; O, 10.57; S, 5.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AZD-1175; AZD1175; AZD 1175

IUPAC/Chemical Name

1-Propanesulfonic acid, 3,3,3-trifluoro-, 4-(1-(2,4-dichlorophenyl)-4-methyl-3-((1-piperidinylamino)carbonyl)-1H-pyrazol-5-yl)phenyl ester

InChi Key

AUAVZPQYSXVTLQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H25Cl2F3N4O4S/c1-16-22(24(35)32-33-12-3-2-4-13-33)31-34(21-10-7-18(26)15-20(21)27)23(16)17-5-8-19(9-6-17)38-39(36,37)14-11-25(28,29)30/h5-10,15H,2-4,11-14H2,1H3,(H,32,35)

SMILES Code

Cc1c(nn(c2ccc(Cl)cc2Cl)c1c3ccc(OS(=O)(=O)CCC(F)(F)F)cc3)C(=O)NN4CCCCC4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 605.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Tannergren C, Karlsson E, Sigfridsson K, Lindfors L, Ku A, Polentarutti B, Carlert S. Biopharmaceutic Profiling of Salts to Improve Absorption of Poorly Soluble Basic Drugs. J Pharm Sci. 2016 Nov;105(11):3314-3323. doi: 10.1016/j.xphs.2016.07.016. Epub 2016 Sep 13. PMID: 27637320.