Azastene | CAS# 13074-00-5 | Biochemical

MedKoo Cat#: 575185 | Name: Azastene

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azastene is a progesterone antagonist that has been shown to inhibit ovarian & adrenal steroidogenesis in rats.

Chemical Structure

Azastene

CAS#13074-00-5

Theoretical Analysis

MedKoo Cat#: 575185

Name: Azastene

CAS#: 13074-00-5

Chemical Formula: C23H33NO2

Exact Mass: 355.2511

Molecular Weight: 355.52

Elemental Analysis: C, 77.70; H, 9.36; N, 3.94; O, 9.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Azastene; Isoxazol; WIN 17625; WIN17625; WIN-17625

IUPAC/Chemical Name

(1S,3aS,3bR,10aR,10bS,12aS)-1,6,6,10a,12a-pentamethyl-2,3,3a,3b,4,6,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol

InChi Key

AXLOCHLTNQDFFS-BESJYZOMSA-N

InChi Code

InChI=1S/C23H33NO2/c1-20(2)18-7-6-15-16(21(18,3)12-14-13-24-26-19(14)20)8-10-22(4)17(15)9-11-23(22,5)25/h7,13,15-17,25H,6,8-12H2,1-5H3/t15-,16+,17+,21-,22+,23+/m1/s1

SMILES Code

O[C@@]1(C)CC[C@]2([H])[C@]1(C)CC[C@]3([H])[C@@]4(C)CC5=C(C(C)(C)C4=CC[C@@]23[H])ON=C5

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 355.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Asch RH, Smith CG, Siler-Khodr TM, Bartke A. Luteolytic effect of azastene in the nonhuman primate. Obstet Gynecol. 1982 Mar;59(3):303-8. PMID: 7078876. 2. Creange JE, Schane HP, Anzalone AJ, Potts GO. Interruption of pregnancy in rats by azastene, an inhibitor of ovarian and adrenal steroidogenesis. Fertil Steril. 1978 Jul;30(1):86-90. PMID: 680188.