Buclizine free base | CAS#82-95-1 | antihistamine

MedKoo Cat#: 591415 | Name: Buclizine

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.

Chemical Structure

Buclizine

CAS#82-95-1 (free base)

Theoretical Analysis

MedKoo Cat#: 591415

Name: Buclizine

CAS#: 82-95-1 (free base)

Chemical Formula: C28H33ClN2

Exact Mass: 432.2332

Molecular Weight: 433.04

Elemental Analysis: C, 77.66; H, 7.68; Cl, 8.19; N, 6.47

Price and Availability

Size	Price	Availability
100mg	USD 350.00	2 Weeks
250mg	USD 650.00	2 Weeks
1g	USD 1,450.00	2 Weeks

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Related CAS #

129-74-8 (HCl) 82-95-1 (free base)

Synonym

Buclizine; Histabutizine; Histabutyzine

IUPAC/Chemical Name

1-(4-(tert-butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine

InChi Key

MOYGZHXDRJNJEP-UHFFFAOYSA-N

InChi Code

InChI=1S/C28H33ClN2/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24/h4-16,27H,17-21H2,1-3H3

SMILES Code

CC(C1=CC=C(CN2CCN(C(C3=CC=C(Cl)C=C3)C4=CC=CC=C4)CC2)C=C1)(C)C

Appearance

Purity

>97% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 433.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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