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MedKoo Cat#: 575105 | Name: Atorvastatin lysine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Atorvastatin lysine is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor.

Chemical Structure

Atorvastatin lysine
Atorvastatin lysine
CAS#609843-23-4 (lysine)

Theoretical Analysis

MedKoo Cat#: 575105

Name: Atorvastatin lysine

CAS#: 609843-23-4 (lysine)

Chemical Formula: C39H49FN4O7

Exact Mass: 704.3585

Molecular Weight: 704.84

Elemental Analysis: C, 66.46; H, 7.01; F, 2.70; N, 7.95; O, 15.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
134523-03-8 (calcium) 344423-98-9 (calcium trihydrate) 134523-00-5 (free acid) 134523-01-6 (sodium) 874114-41-7 (magnesium) 1035609-19-8 (magnesium trihydrate) 609843-23-4 (lysine) 1072903-92-4 (strontium)
Synonym
Atorvastatin lysine
IUPAC/Chemical Name
L-Lysine, (betaR,deltaR)-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoate (1:1)
InChi Key
OGVHFUBTPHZMJC-KLMFVFGRSA-N
InChi Code
1S/C33H35FN2O5.C6H14N2O2/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;7-4-2-1-3-5(8)6(9)10/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);5H,1-4,7-8H2,(H,9,10)/t26-,27-;5-/m10/s1
SMILES Code
CC(C)c1c(C(=O)Nc2ccccc2)c(c3ccccc3)c(c4ccc(F)cc4)n1CC[C@@H](O)C[C@@H](O)CC(=O)O.NCCCC[C@H](N)C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 704.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yang B, Sun J, Yuan Y, Sun Z. Effects of atorvastatin on autophagy in skeletal muscles of diabetic rats. J Diabetes Investig. 2018 Jul;9(4):753-761. doi: 10.1111/jdi.12789. Epub 2018 Jan 30. PubMed PMID: 29245171; PubMed Central PMCID: PMC6031525. 2: Qiu S, Zhuo W, Sun C, Su Z, Yan A, Shen L. Effects of atorvastatin on chronic subdural hematoma: A systematic review. Medicine (Baltimore). 2017 Jun;96(26):e7290. doi: 10.1097/MD.0000000000007290. Review. PubMed PMID: 28658127; PubMed Central PMCID: PMC5500049. 3: El-Nabarawi N, El-Wakd M, Salem M. Atorvastatin, a double weapon in osteoporosis treatment: an experimental and clinical study. Drug Des Devel Ther. 2017 May 2;11:1383-1391. doi: 10.2147/DDDT.S133020. eCollection 2017. PubMed PMID: 28496308; PubMed Central PMCID: PMC5422318.