Atorvastatin Sodium | CAS#134523-01-6 | HMG-CoA Reductase Inhibitor

MedKoo Cat#: 593039 | Name: Atorvastatin Sodium

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Atorvastatin sodium is a competitive inhibitor of HMG-CoA reductase, increasing expression of low-density lipoprotein receptors (LDL receptors) on hepatocytes. Atorvastatin sodium pretreatment attenuates ischemic brain edema by suppressing aquaporin 4.

Chemical Structure

Atorvastatin Sodium

CAS#134523-01-6 (sodium)

Theoretical Analysis

MedKoo Cat#: 593039

Name: Atorvastatin Sodium

CAS#: 134523-01-6 (sodium)

Chemical Formula: C33H34FN2NaO5

Exact Mass: 0.0000

Molecular Weight: 580.63

Elemental Analysis: C, 68.26; H, 5.90; F, 3.27; N, 4.82; Na, 3.96; O, 13.78

Price and Availability

Size	Price	Availability
250mg	USD 450.00	2 Weeks
500mg	USD 800.00	2 Weeks
1g	USD 1,350.00	2 Weeks

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Related CAS #

134523-03-8 (calcium) 344423-98-9 (calcium trihydrate) 134523-00-5 (free acid) 134523-01-6 (sodium) 874114-41-7 (magnesium) 1035609-19-8 (magnesium trihydrate) 609843-23-4 (lysine) 1072903-92-4 (strontium)

Synonym

Atorvastatin Sodium; Lipitor

IUPAC/Chemical Name

Sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

InChi Key

VVRPOCPLIUDBSA-CNZCJKERSA-M

InChi Code

InChI=1S/C33H35FN2O5.Na/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/q;+1/p-1/t26-,27-;/m1./s1

SMILES Code

CC(C)c1c(c(c(n1CC[C@H](C[C@H](CC(=O)[O-])O)O)c2ccc(cc2)F)c3ccccc3)C(=O)Nc4ccccc4.[Na+]

Appearance

Pale Yellow Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 580.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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