MedKoo Cat#: 412548 | Name: Quindoxin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quindoxin is a biochemical

Chemical Structure

Quindoxin
Quindoxin
CAS#2423-66-7

Theoretical Analysis

MedKoo Cat#: 412548

Name: Quindoxin

CAS#: 2423-66-7

Chemical Formula: C8H6N2O2

Exact Mass: 162.0429

Molecular Weight: 162.15

Elemental Analysis: C, 59.26; H, 3.73; N, 17.28; O, 19.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Quindoxin; NSC21653; NSC-21653 NSC 21653
IUPAC/Chemical Name
quinoxaline 1,4-dioxide
InChi Key
CKIHZSGJPSDCNC-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H6N2O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H
SMILES Code
O=n(ccn1=O)c2c1cccc2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 162.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Suter W, Rosselet A, Knüsel F. Mode of action of quindoxin and substituted quinoxaline-di-N-oxides on Escherichia coli. Antimicrob Agents Chemother. 1978 May;13(5):770-83. doi: 10.1128/aac.13.5.770. PMID: 352264; PMCID: PMC352330. 2: Beutin L, Preller E, Kowalski B. Mutagenicity of quindoxin, its metabolites, and two substituted quinoxaline-di-N-oxides. Antimicrob Agents Chemother. 1981 Sep;20(3):336-43. doi: 10.1128/aac.20.3.336. PMID: 7030199; PMCID: PMC181697. 3: Zaynoun S, Johnson BE, Frain-Bell W. The investigation of quindoxin photosensitivity. Contact Dermatitis. 1976 Dec;2(6):343-52. doi: 10.1111/j.1600-0536.1976.tb03073.x. PMID: 1032128. 4: Hennessey TD, Edwards JR. Antibacterial properties of quindoxin: a new growth-promoting agent. Vet Rec. 1972 Feb 12;90(7):187-91. doi: 10.1136/vr.90.7.187. PMID: 4553051. 5: Frain-Bell W, Gardiner J. Photocontact dermatitis due to quindoxin. Contact Dermatitis. 1975 Aug;1(4):256-7. doi: 10.1111/j.1600-0536.1975.tb05411.x. PMID: 139237. 6: Voogd CE, van der Stel JJ, Jacobs JJ. The mutagenic action of quindoxin, carbadox, olaquindox and some other N-oxides on bacteria and yeast. Mutat Res. 1980 Jul;78(3):233-42. doi: 10.1016/0165-1218(80)90104-4. PMID: 7001216. 7: Scheutwinkel-Reich M, vd Hude W. Sister-chromatid exchange in Chinese hamster V79 cells exposed to quindoxin, carbadox and olaquindox. Mutat Res. 1984 Apr;139(4):199-202. doi: 10.1016/0165-7992(84)90128-3. PMID: 6717485. 8: de Vries H, Bojarski J, Donker AA, Bakri A, Beyersbergen van Henegouwen GM. Photochemical reactions of quindoxin, olaquindox, carbadox and cyadox with protein, indicating photoallergic properties. Toxicology. 1990 Jul;63(1):85-95. doi: 10.1016/0300-483x(90)90071-n. PMID: 2382272. 9: Scott KW, Dawson TA. Photo-contact dermatitis arising from the presence of quindoxin in animal feeding stuffs. Br J Dermatol. 1974 May;90(5):543-6. doi: 10.1111/j.1365-2133.1974.tb06450.x. PMID: 4833790. 10: Inbaraj JJ, Motten AG, Chignell CF. Photochemical and photobiological studies of tirapazamine (SR 4233) and related quinoxaline 1,4-Di-N-oxide analogues. Chem Res Toxicol. 2003 Feb;16(2):164-70. doi: 10.1021/tx0256073. PMID: 12588187.