XP5 is a potent HDAC6 inhibitor with an IC50 of 31 nM and excellent HDAC6 selectivity. XP5 also displayed high antiproliferative activity against various cancer cell lines including the HDACi-resistant YCC3/7 gastric cancer cells (IC50 = 0.16−2.31 μM), better than CAY10603.
MedKoo Cat#: 465752
Name: XP5
CAS#: unknown
Chemical Formula: C19H25N3O5S
Exact Mass: 407.1515
Molecular Weight: 407.49
Elemental Analysis: C, 56.00; H, 6.18; N, 10.31; O, 19.63; S, 7.87
The following data is based on the product molecular weight 407.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |