Synonym
Troclosene (free base); CDB-60; CDB60; CDB 60
IUPAC/Chemical Name
1,3-dichloro-1,3,5-triazinane-2,4,6-trione
InChi Key
CEJLBZWIKQJOAT-UHFFFAOYSA-N
InChi Code
InChI=1S/C3HCl2N3O3/c4-7-1(9)6-2(10)8(5)3(7)11/h(H,6,9,10)
SMILES Code
ClN1C(NC(N(C1=O)Cl)=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
197.96
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Hosein I, Madeloso R, Nagaratnam W, Villamaria F, Stock E, Jinadatha C. Evaluation of a pulsed xenon ultraviolet light device for isolation room disinfection in a United Kingdom hospital. Am J Infect Control. 2016 Sep 1;44(9):e157-61. doi: 10.1016/j.ajic.2016.01.044. Epub 2016 Mar 31. PMID: 27040562.
2: Motta O, Zarrella I, Cucciniello R, Capunzo M, De Caro F. A new strategy to control the proliferation of microorganisms in solid hospital waste and the diffusion of nosocomial infections. Infez Med. 2018 Sep 1;26(3):210-215. PMID: 30246763.
3: Mao Y, Zhang L, Dong H. Formation of trihalomethanes in swimming pool waters using sodium dichloroisocyanurate as an alternative disinfectant. Water Sci Technol. 2018 Nov;78(8):1633-1641. doi: 10.2166/wst.2018.439. PMID: 30500787.
4: Duarte ALA, do Rosário DKA, Oliveira SBS, de Souza HLS, de Carvalho RV, Carneiro JCS, Silva PI, Bernardes PC. Ultrasound improves antimicrobial effect of sodium dichloroisocyanurate to reduce Salmonella Typhimurium on purple cabbage. Int J Food Microbiol. 2018 Mar 23;269:12-18. doi: 10.1016/j.ijfoodmicro.2018.01.007. Epub 2018 Jan 8. PMID: 29353020.
5: Naser AM, Higgins EM, Arman S, Ercumen A, Ashraf S, Das KK, Rahman M, Luby SP, Unicomb L. Effect of Groundwater Iron on Residual Chlorine in Water Treated with Sodium Dichloroisocyanurate Tablets in Rural Bangladesh. Am J Trop Med Hyg. 2018 Apr;98(4):977-983. doi: 10.4269/ajtmh.16-0954. Epub 2018 Feb 8. PMID: 29436334; PMCID: PMC5928807.
6: Vitali M, Protano C, Agolini G. Advantages of sodium hypochlorite or sodium dichloroisocyanurate disinfection for teats and bottles in newborn infants' feeding. Public Health Nurs. 2008 Mar-Apr;25(2):103-5. doi: 10.1111/j.1525-1446.2008.00686.x. PMID: 18294178.
7: Hammond BG, Barbee SJ, Inoue T, Ishida N, Levinskas GJ, Stevens MW, Wheeler AG, Cascieri T. A review of toxicology studies on cyanurate and its chlorinated derivatives. Environ Health Perspect. 1986 Nov;69:287-92. doi: 10.1289/ehp.8669287. PMID: 3545805; PMCID: PMC1474314.
8: Clasen T, Edmondson P. Sodium dichloroisocyanurate (NaDCC) tablets as an alternative to sodium hypochlorite for the routine treatment of drinking water at the household level. Int J Hyg Environ Health. 2006 Mar;209(2):173-81. doi: 10.1016/j.ijheh.2005.11.004. Epub 2006 Jan 4. PMID: 16387550.
9: Malik DJ, Patel KV, Clokie MR, Shama G. On the difficulties of isolating Clostridium difficile from hospital environments. J Hosp Infect. 2013 Jun;84(2):181-3. doi: 10.1016/j.jhin.2013.02.020. Epub 2013 May 3. PMID: 23643391.
10: Joshi LT, Welsch A, Hawkins J, Baillie L. The effect of hospital biocide sodium dichloroisocyanurate on the viability and properties of Clostridium difficile spores. Lett Appl Microbiol. 2017 Sep;65(3):199-205. doi: 10.1111/lam.12768. Epub 2017 Aug 6. PMID: 28639362.