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MedKoo Cat#: 412398 | Name: Carriomycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carriomycin is a polyether antibiotic from Streptomyces hygroscopicus.

Chemical Structure

Carriomycin
Carriomycin
CAS#65978-43-0

Theoretical Analysis

MedKoo Cat#: 412398

Name: Carriomycin

CAS#: 65978-43-0

Chemical Formula: C47H80O15

Exact Mass: 884.5497

Molecular Weight: 885.14

Elemental Analysis: C, 63.78; H, 9.11; O, 27.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Carriomycin; T42082; T 42082; T-42082
IUPAC/Chemical Name
(2R)-2-((2S,3S,4R,5R,6S)-6-(((2R,3R,4R,7S,9R,10R)-2-((2S,2'R,5'R)-5'-((3S,5R,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)octahydro-[2,2'-bifuran]-5-yl)-3,9-dimethoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl)methyl)-4-(((2S,5S,6R)-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5-dimethyltetrahydro-2H-pyran-2-yl)propaneperoxoic acid
InChi Key
WWIQNJAWIWZDGY-CPCSCANYSA-N
InChi Code
InChI=1S/C47H80O15/c1-23-20-24(2)46(10,49)60-40(23)35-15-14-33(55-35)34-16-18-38(56-34)45(9)43(53-13)29(7)47(62-45)28(6)37(52-12)22-31(59-47)21-36-25(3)41(26(4)42(57-36)27(5)44(48)61-50)58-39-19-17-32(51-11)30(8)54-39/h23-43,49-50H,14-22H2,1-13H3/t23-,24+,25+,26+,27+,28+,29+,30+,31+,32-,33+,34-,35+,36-,37+,38?,39+,40?,41+,42-,43+,45+,46-,47?/m0/s1
SMILES Code
CO[C@H]1CC[C@H](O[C@@H]1C)O[C@@H]2[C@@H]([C@@H](O[C@@H]([C@@H]2C)[C@H](C(OO)=O)C)C[C@@H]3C[C@H]([C@H](C4(O[C@](C5CC[C@@H]([C@H]6CC[C@H](C7O[C@](O)([C@@H](C[C@@H]7C)C)C)O6)O5)([C@@H]([C@H]4C)OC)C)O3)C)OC)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 885.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Imada A, Nozaki Y, Hasegawa T, Mizuta E, Igarasi S, Yoneda M. Carriomycin, a new polyether antibiotic produced by Streptomyces hygroscopicus. J Antibiot (Tokyo). 1978 Jan;31(1):7-14. doi: 10.7164/antibiotics.31.7. PMID: 342475. 2: Mitani M, Otake N. Studies on the ionophorous antibiotics. XV The monovalent cation selective ionophorous activities of carriomycin, lonomycin and etheromycin. J Antibiot (Tokyo). 1978 Aug;31(8):750-5. doi: 10.7164/antibiotics.31.750. PMID: 690008. 3: Mizoue K, Seto H, Mizutani T, Yamagishi M, Kawashima A, Omura S, Ozeki M, Otake N. Studies on the ionophorous antibiotics. XXV. The assignments of the 13C-NMR spectra of dianemycin and lenoremycin. J Antibiot (Tokyo). 1980 Feb;33(2):144-56. doi: 10.7164/antibiotics.33.144. PMID: 7380725. 4: Ogura M, Tanaka T, Furihata K, Shimazu A, Otake N. Induction of antibiotic production with ethidium bromide in Streptomyces hygroscopicus. J Antibiot (Tokyo). 1986 Oct;39(10):1443-9. doi: 10.7164/antibiotics.39.1443. PMID: 3781913. 5: Siegel MM, McGahren WJ, Tomer KB, Chang TT. Applications of fast atom bombardment mass spectrometry and fast atom bombardment mass spectrometry-mass spectrometry to the maduramicins and other polyether antibiotics. Biomed Environ Mass Spectrom. 1987 Jan;14(1):29-38. doi: 10.1002/bms.1200140108. PMID: 2952192. 6: Mitani M, Otake N. Studies on the ionophorous antibiotics. XVI. The ionophore-mediated calcium transport and concomitant osmotic swelling of mitochondria. J Antibiot (Tokyo). 1978 Sep;31(9):888-93. doi: 10.7164/antibiotics.31.888. PMID: 711630. 7: Sasaki J, Mizoue K, Morimoto S, Omura S. Microbial glycosylation of macrolide antibiotics by Streptomyces hygroscopicus ATCC 31080 and distribution of a macrolide glycosyl transferase in several Streptomyces strains. J Antibiot (Tokyo). 1996 Nov;49(11):1110-8. doi: 10.7164/antibiotics.49.1110. PMID: 8982340.